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Case Reports
. 2020 Jul 16;13(2):853-856.
doi: 10.1159/000508531. eCollection 2020 May-Aug.

Abdominal Mass Caused Failure to Thrive in a Young Boy: Mixed-Type Localized Retroperitoneal Castleman Disease

Bahar Ashjaei  1 , Afshar Ghamari Khameneh  2 , Gisoo Darban Hosseini Amirkhiz  3
Affiliations
Case Reports

Abdominal Mass Caused Failure to Thrive in a Young Boy: Mixed-Type Localized Retroperitoneal Castleman Disease

Bahar Ashjaei et al. Case Rep Oncol. .

Abstract

Castleman disease is a rare cause of retroperitoneal mass in children. Clinical presentation and laboratory findings are usually nonspecific. Imaging shows features of a hypervascular or soft tissue mass. We present a 12-year-old boy who complained of frequent colds, fatigue, and failure to gain weight for the past 4 years who was referred to our hospital. Anemia and hypergammaglobulinemia were revealed in laboratory tests. Imaging showed a well-delineated retroperitoneal soft tissue mass with intense homogenous enhancement at the midline below the aortic bifurcation. The histopathological features were consistent with mixed type unicentric Castleman disease. Surgical removal was curative. Our patient's hematological abnormalities resolved, and he gained 10 kg in the next 4 weeks after the operation and reached the 25-50th percentile for his age.

Keywords: Anemia; Castleman disease; Failure to thrive; Pediatric; Retroperitoneum.

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Conflict of interest statement

The authors have no conflicts of interest relevant to this article to disclose.

Figures

Fig. 1
Fig. 1
a Axial CT scan, there is a retroperitoneal homogeneously enhancing mass (*) with well-defined borders. b Multiple satellite small lymph nodes are noted. c A sagittal reformatted CT scan confirmed the position of the mass (*) below the aortic bifurcation.
Fig. 2
Fig. 2
An abdominal MRI demonstrated a well-circumscribed homogenous retroperitoneal mass (*), isointense on T1-weighted image (a) and hyperintense on T2-weighted image (b) with enhancement (c, d).
See this image and copyright information in PMC

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