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Review
. 2020 Mar 28;7(3):320-327.
doi: 10.1016/j.gendis.2020.02.001. eCollection 2020 Sep.

Progress in hepatectomy for hepatocellular carcinoma and peri-operation management

Hao Chen  1   2 , Weidong Jia  1   2
Affiliations
Review

Progress in hepatectomy for hepatocellular carcinoma and peri-operation management

Hao Chen et al. Genes Dis. .

Abstract

The global incidence of liver cancer continues to grow. Liver cancer, especially hepatocellular carcinoma, has high recurrence and mortality rates. Here, we review the past decade's diagnostic, therapeutic, and management strategies for hepatocellular carcinoma, and summarize new patient management approaches, including enhanced recovery after surgery, targeted therapy, and immunotherapy. We compare traditional and innovative management methods, which comprise developments in precision medicine, and consider their limitations. Ongoing innovation and technological advances enable surgeons to gain deeper understandings of the multidimensionality of hepatocellular carcinoma, thereby promoting the continuous development of precision therapy.

Keywords: Enhanced recovery after surgery; Hepatectomy; Hepatocellular carcinoma; Precision medicine; Treatment.

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References

    1. Bray F., Ferlay J., Soerjomataram I., Siegel R.L., Torre L.A., Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018;68(6):394–424. - PubMed
    1. Ramdass R., Lekwuwa G.U., Mitchell D. Diaphragmatic involvement without bulbar dysfunction or features to suggest amyotrophic lateral sclerosis in brachial amyotrophic diplegia. Muscle Nerve. 2009;40(6):1066–1067. - PubMed
    1. Llovet J.M., Montal R., Sia D., Finn R.S. Molecular therapies and precision medicine for hepatocellular carcinoma. Nat Rev Clin Oncol. 2018;15(10):599–616. - PMC - PubMed
    1. Llovet J.M., Zucman-Rossi J., Pikarsky E. Hepatocellular carcinoma. Nat Rev Dis Primers. 2016;2:16018. - PubMed
    1. Kanwal F., Singal A.G. Surveillance for hepatocellular carcinoma: current best practice and future direction. Gastroenterology. 2019;157(1):54–64. - PMC - PubMed

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