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Case Reports
. 2021 Feb;69(2):394-397.
doi: 10.1007/s11748-020-01475-3. Epub 2020 Sep 4.

Thymic lipofibroadenoma accompanied with largish calcifications

Affiliations
Case Reports

Thymic lipofibroadenoma accompanied with largish calcifications

Shuhei Hakiri et al. Gen Thorac Cardiovasc Surg. 2021 Feb.

Abstract

Thymic lipofibroadenomas are extremely rare; their radiological features have never been reported. We report the first case of a lipofibroadenoma with some largish calcifications mimicking a teratoma. A 28-year-old man had an anterior mediastinal tumor with some calcifications on preoperative computed tomography, which was suspected to be a mature teratoma and resected through robot-assisted thoracic surgery. This tumor had strands of epithelial cells separated by abundant fibrous stroma containing fat cells and was thus diagnosed as a lipofibroadenoma. He was well without any recurrence 6 months postoperatively. Largish calcifications on preoperative computed tomography make distinguishing between teratomas and lipfibroadenomas difficult.

Keywords: Calcification; Lipofibroadenoma; Rare thymomas.

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References

    1. Chen G, Chalabreysse L. Other rare thymomas. In: Travis WD, Brambilla E, Burke AP, Marx A, Nicholson AG, editors. WHO Classification of Tumours of Lung, Pleura, Thymus and Heart. 4th ed. Lyon: IARC; 2015. p. 209–211.
    1. Kuo T, Shih LY. Histologic types of thymoma associated with pure red cell aplasia: a study of five cases including a composite tumor of organoid thymoma associated with an unusual lipofibroadenoma. Int J Surg Pathol. 2001;9:29–35. - DOI
    1. Aydin Y, Sipal S, Celik M, et al. A rare thymoma type presenting as a giant intrathoracic tumor: lipofibroadenoma. Eurasian J Med. 2012;44:176–8. - DOI
    1. Qu G, Yu G, Zhang Q, et al. Lipofibroadenoma of the thymus: a case report. Diagn Pathol. 2013;8:117. - PubMed - PMC
    1. Makdisi G, Roden AC, Shen KR. Successful resection of giant mediastinal lipofibroadenoma of the thymus by video-assisted thoracoscopic surgery. Ann Thorac Surg. 2015;100:698–700. - DOI

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