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Clinical Trial
. 1988 Apr;51(4):529-33.
doi: 10.1136/jnnp.51.4.529.

Parkinson's disease: an open label trial of pergolide in patients failing bromocriptine therapy

S A Factor  1 , J R Sanchez-Ramos, W J Weiner
Affiliations
Clinical Trial

Parkinson's disease: an open label trial of pergolide in patients failing bromocriptine therapy

S A Factor et al. J Neurol Neurosurg Psychiatry. 1988 Apr.

Abstract

Sixty-three patients with Parkinson's disease who failed bromocriptine therapy for various reasons were treated in an open-label trial of pergolide. The data were evaluated in a retrospective manner. Forty-six percent had a good response and tolerated the pergolide. A comparison of the outcomes regarding response and toxicity revealed that bromocriptine and pergolide act differently in individual patients. A trial of pergolide in Parkinsonian patients failing bromocriptine therapy may be therapeutically useful.

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