Severe Acute Respiratory Syndrome Coronavirus 2 RNA in Plasma Is Associated With Intensive Care Unit Admission and Mortality in Patients Hospitalized With Coronavirus Disease 2019
- PMID: 32888003
- PMCID: PMC7499533
- DOI: 10.1093/cid/ciaa1338
Severe Acute Respiratory Syndrome Coronavirus 2 RNA in Plasma Is Associated With Intensive Care Unit Admission and Mortality in Patients Hospitalized With Coronavirus Disease 2019
Abstract
The clinical significance of severe acute respiratory syndrome coronavirus 2 RNA in the circulation is unknown. In this prospective cohort study, we detected viral RNA in the plasma of 58 of 123 (47%) patients hospitalized with coronavirus disease 2019. RNA was detected more frequently, and levels were higher, in patients who were admitted to the intensive care unit and/or died.
Keywords: COVID-19; RNAemia; SARS-CoV-2; antibodies; viral load.
© The Author(s) 2020. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.
Comment in
-
Carving Out a Niche for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Plasma RNA Testing.Clin Infect Dis. 2021 Aug 2;73(3):e803-e804. doi: 10.1093/cid/ciaa1412. Clin Infect Dis. 2021. PMID: 32941602 Free PMC article. No abstract available.
Comment on
-
Carving Out a Niche for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Plasma RNA Testing.Clin Infect Dis. 2021 Aug 2;73(3):e803-e804. doi: 10.1093/cid/ciaa1412. Clin Infect Dis. 2021. PMID: 32941602 Free PMC article. No abstract available.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
Miscellaneous