Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2020 Sep 3;27(3):352-353.
doi: 10.1016/j.stem.2020.08.008.

Straight to the X: Modeling Human X Chromosome Inactivation in hESCs by FGF Signal Blockade

Emmanuel Cazottes  1 , Claire Rougeulle  2
Affiliations
Free article
Comment

Straight to the X: Modeling Human X Chromosome Inactivation in hESCs by FGF Signal Blockade

Emmanuel Cazottes et al. Cell Stem Cell. .
Free article

Abstract

In this issue of Cell Stem Cell, An et al. (2020) provide a model to study human X chromosome inactivation. They followed X chromosome activity and traced cellular heterogeneity in naive hESCS, showed that it is caused by incomplete blockade of FGF-signaling, and in doing so isolated cells resembling pre-implantation epiblasts.

PubMed Disclaimer

Comment on

LinkOut - more resources