Anaesthetic-induced developmental neurotoxicity on (neuro)steroids
- PMID: 32891411
- DOI: 10.1016/j.bja.2020.08.008
Anaesthetic-induced developmental neurotoxicity on (neuro)steroids
Keywords: alphaxalone; anaesthetic mechanism; apoptosis; calcium channel; gamma-aminobutyric acid; neurosteroid; neurotoxicity.
Conflict of interest statement
Declarations of interest The author declares that he has no conflicts of interest.
Comment on
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The T-type calcium channel isoform Cav3.1 is a target for the hypnotic effect of the anaesthetic neurosteroid (3β,5β,17β)-3-hydroxyandrostane-17-carbonitrile.Br J Anaesth. 2021 Jan;126(1):245-255. doi: 10.1016/j.bja.2020.07.022. Epub 2020 Aug 25. Br J Anaesth. 2021. PMID: 32859366 Free PMC article.
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