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. 2020 Oct:82:179-181.
doi: 10.1016/j.ijsu.2020.08.038. Epub 2020 Sep 4.

Dexamethasone to combat cytokine storm in COVID-19: Clinical trials and preliminary evidence

Khan Sharun  1 , Ruchi Tiwari  2 , Jaideep Dhama  3 , Kuldeep Dhama  4
Affiliations

Dexamethasone to combat cytokine storm in COVID-19: Clinical trials and preliminary evidence

Khan Sharun et al. Int J Surg. 2020 Oct.
No abstract available

Keywords: COVID-19; Clinical trials; Cytokine storm; Dexamethasone; SARS-CoV-2; Therapeutics.

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Conflict of interest statement

All authors declare that there exist no commercial or financial relationships that could, in any way, lead to a potential conflict of interest.

References

    1. Roshanravan N., Seif F., Ostadrahimi A., et al. Targeting cytokine storm to manage patients with COVID-19: a mini-review. Arch. Med. Res. 2020:1–5. doi: 10.1016/j.arcmed.2020.06.012. - DOI - PMC - PubMed
    1. Theoharides T.C., Conti P. Dexamethasone for COVID-19? Not so fast. J. Biol. Regul. Homeost. Agents. 2020 Jun 4;34(3):1–5. doi: 10.23812/20-EDITORIAL_1-5. - DOI - PubMed
    1. Abdolahi N., Kaheh E., Golsha R., et al. Letter to the editor: efficacy of different methods of combination regimen administrations including dexamethasone, intravenous immunoglobulin, and interferon-beta to treat critically ill COVID-19 patients: a structured summary of a study protocol for a randomized controlled trial. Trials. 2020 Jun 19;21(1):549. doi: 10.1186/s13063-020-04499-5. - DOI - PMC - PubMed
    1. Lim M.A., Pranata R. Worrying situation regarding the use of dexamethasone for COVID-19. Ther. Adv. Respir. Dis. 2020 Jan-Dec;14 doi: 10.1177/1753466620942131. 1753466620942131. - DOI - PMC - PubMed
    1. Rhen T., Cidlowski J.A. Antiinflammatory action of glucocorticoids--new mechanisms for old drugs. N. Engl. J. Med. 2005 Oct 20;353(16):1711–1723. doi: 10.1056/NEJMra050541. - DOI - PubMed