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Review
. 1988 Apr:77:29-31.
doi: 10.1289/ehp.887729.

Lesions of testis and epididymis associated with prenatal diethylstilbestrol exposure

B C Bullock  1 , R R Newbold, J A McLachlan
Affiliations
Review

Lesions of testis and epididymis associated with prenatal diethylstilbestrol exposure

B C Bullock et al. Environ Health Perspect. 1988 Apr.

Abstract

Cryptorchidism and retention of Müllerian duct structures occur with high frequency among the male offspring of CD-1 mice treated with 100 micrograms diethylstilbestrol/kg body weight on days 9 through 16 of pregnancy. Hyperplasia of the rete testis and Müllerian duct structures were found in many of the DES-treated male mice, as was a low but significant number of reproductive tract neoplasms.

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