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. 2020 Sep 4;8(9):1358.
doi: 10.3390/microorganisms8091358.

Epidemiology of Cryptosporidiosis in France from 2017 to 2019

Damien Costa  1   2   3 , Romy Razakandrainibe  2   3 , Stéphane Valot  4   5 , Margot Vannier  6 , Marc Sautour  5 , Louise Basmaciyan  4   5 , Gilles Gargala  1   2   3 , Venceslas Viller  3 , Denis Lemeteil  1 , Jean-Jacques Ballet  2 ; French National Network on Surveillance of Human Cryptosporidiosis; Frédéric Dalle  4   5 , Loïc Favennec  1   2   3
Collaborators, Affiliations

Epidemiology of Cryptosporidiosis in France from 2017 to 2019

Damien Costa et al. Microorganisms. .

Abstract

Cryptosporidiosis is currently recognized worldwide as a leading cause of moderate to severe diarrhea. In Europe, large water- and foodborne outbreaks have been reported, highlighting the widespread distribution of the parasite and its important health impact. Surveillance networks have been progressively set up and the aim of this study was to present recent epidemiological data obtained in France from 2017 to 2019 by the National Reference Center-Expert Laboratory of cryptosporidiosis (Centre National de Référence-Laboratoire Expert cryptosporidioses CNR-LE). Data were obtained from online reports of volunteer network participants and stools were sent to the CNR-LE for species identification and GP60 genotyping. During this period, data from 750 online reports were available. Cryptosporidiosis occurred predominantly in young children (<5 years old) and in young adults, especially during late summer. Most patients were immunocompetent (60%), and deaths were reported only in immunocompromised patients. Cryptosporidium parvum was largely predominant (72% of cases) over C. hominis (24%) and some other uncommon species. C. parvum GP60 subtypes IIa and IId were the most represented, which suggests frequent zoonotic transmission. For C. hominis, subtypes IbA10G2 and IaA22R2 were predominant.

Keywords: France; cryptosporidiosis; epidemiology.

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Conflict of interest statement

The authors declare no conflict of interest. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results.

Figures

Figure 1
Figure 1
Annual distribution of cryptosporidiosis cases in France from 2017 to 2019.
Figure 2
Figure 2
Demography of cryptosporidiosis reported cases from 2017 to 2019 in tertiary care public hospitals in France.
Figure 3
Figure 3
Demography of cryptosporidiosis reported cases from 2017 to 2019 in private laboratories in France.
Figure 4
Figure 4
Distribution of GP60 subtypes of C. hominis/C. parvum species among reported cases in France from 2017 to 2019.
See this image and copyright information in PMC

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