Review
Testing for SARS-CoV-2 (COVID-19): A General Review
Affiliations
- PMID: 32900007
Item in Clipboard
Review
Testing for SARS-CoV-2 (COVID-19): A General Review
R I Med J (2013).
.
Free article
Abstract
The rampant COVID-19 pandemic has strained the testing capabilities of healthcare centers across the country. Several nucleic acid and serologic assays are available or currently being developed to meet the growing demand for large-scale testing. This review summarizes the developments of commonly used testing methods and their strategic use in clinical diagnosis and epidemiologic surveillance. This review will cover the basic virology of SARS-CoV-2, nucleic acid amplification testing, serology, antigen testing, as well as newer testing methods such as CRISPR-based assays.
Keywords: COVID-19; RT-PCR; serology testing.
Similar articles
-
Special Issue on Diagnostic Testing for Severe Acute Respiratory Syndrome Coronavirus 2 and Lessons from This Pandemic.J Clin Microbiol. 2020 Jul 23;58(8):e01324-20. doi: 10.1128/JCM.01324-20. Print 2020 Jul 23. J Clin Microbiol. 2020. PMID: 32703896 Free PMC article. No abstract available.
-
Test Agreement between Roche Cobas 6800 and Cepheid GeneXpert Xpress SARS-CoV-2 Assays at High Cycle Threshold Ranges.J Clin Microbiol. 2020 Jul 23;58(8):e01187-20. doi: 10.1128/JCM.01187-20. Print 2020 Jul 23. J Clin Microbiol. 2020. PMID: 32444354 Free PMC article. No abstract available.
-
Selecting a SARS-CoV-2/COVID Molecular Testing Method for Your Laboratory.J Appl Lab Med. 2020 Jul 1;5(4):837-840. doi: 10.1093/jalm/jfaa076. J Appl Lab Med. 2020. PMID: 32761155 Free PMC article.
-
The COVID-19 Diagnostic Dilemma: a Clinician's Perspective.J Clin Microbiol. 2020 Jul 23;58(8):e01287-20. doi: 10.1128/JCM.01287-20. Print 2020 Jul 23. J Clin Microbiol. 2020. PMID: 32703894 Free PMC article. Review.
-
Diagnostic Stewardship: An Essential Element in a Rapidly Evolving COVID-19 Pandemic.Mayo Clin Proc. 2020 Sep;95(9S):S17-S19. doi: 10.1016/j.mayocp.2020.05.039. Epub 2020 Jun 23. Mayo Clin Proc. 2020. PMID: 32807516 Free PMC article. Review. No abstract available.
Cited by
-
Corona exhaustion (CORONEX): COVID-19-induced exhaustion grinding down humanity.Curr Res Behav Sci. 2021 Nov;2:100014. doi: 10.1016/j.crbeha.2021.100014. Epub 2021 Jan 13. Curr Res Behav Sci. 2021. PMID: 38620780 Free PMC article.
-
Monocyte distribution width as a pragmatic screen for SARS-CoV-2 or influenza infection.Sci Rep. 2022 Dec 13;12(1):21528. doi: 10.1038/s41598-022-24978-w. Sci Rep. 2022. PMID: 36513693 Free PMC article.
-
Interleukin-8 as a Biomarker for Disease Prognosis of Coronavirus Disease-2019 Patients.Front Immunol. 2021 Jan 8;11:602395. doi: 10.3389/fimmu.2020.602395. eCollection 2020. Front Immunol. 2021. PMID: 33488599 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Medical
Miscellaneous
