Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2020 Oct;12(5):1223-1231.
doi: 10.1007/s12551-020-00750-0. Epub 2020 Sep 8.

An overview of polymeric nano-biocomposites as targeted and controlled-release devices

Affiliations
Review

An overview of polymeric nano-biocomposites as targeted and controlled-release devices

Muhammad Rahim et al. Biophys Rev. 2020 Oct.

Abstract

In recent years, controlled drug delivery has become an important area of research. Nano-biocomposites can fulfil the necessary requirements of a targeted drug delivery device. This review describes use of polymeric nano-biocomposites in controlled drug delivery devices. Selection of suitable biopolymer and methods of preparation are discussed.

Keywords: Biopolymers; Controlled drug delivery; Nano-biocomposites; Nano-materials.

PubMed Disclaimer

Conflict of interest statement

The authors declare that they have no conflict of interest.

Figures

Fig. 1
Fig. 1
Classification of nano-biocomposites based on a three-dimensional structure
Fig. 2
Fig. 2
Chemical structure of chitosan and alginate
Fig. 3
Fig. 3
Types of nano-biocomposites based on interfacial interactions between monomers of the extended and host polymer

Similar articles

Cited by

References

    1. Abdeen R, Salahuddin N. Modified chitosan-clay nanocomposite as a drug delivery system intercalation and in vitro release of ibuprofen. J Chem. 2013;2013:576370.
    1. Aguzzi C, Capra P, Bonferoni C, Cerezo P, Salcedo I, Sánchez R, Caramella C, Viseras C. Chitosan–silicate biocomposites to be used in modified drug release of 5-aminosalicylic acid (5-ASA) Appl Clay Sci. 2010;50(1):106–111.
    1. Alba CMD, Cota Reguero A, Osuna Barroso FJ, Pavón González E, Perdigón Aller AC, Raffin F. Bionanocomposites based on chitosan intercalation in designed swelling high-charged micas. Sci Rep. 2019;9(1):1–9. - PMC - PubMed
    1. An L, Hu H, Du J, Wei J, Wang L, Yang H, Wu D, Shi H, Li F, Yang S. Paramagnetic hollow silica nanospheres for in vivo targeted ultrasound and magnetic resonance imaging. Biomaterials. 2014;35(20):5381–5392. - PubMed
    1. Ansari AA, Alhoshan M, Alsalhi MS, Aldwayyan AS. Prospects of nanotechnology in clinical immunodiagnostics. Sensors. 2010;10(7):6535–6581. - PMC - PubMed

LinkOut - more resources