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Meta-Analysis
. 2021 Jun;8(3):743-755.
doi: 10.1007/s40615-020-00835-2. Epub 2020 Sep 8.

Impact of Maternal Demographic and Socioeconomic Factors on the Association Between Particulate Matter and Adverse Birth Outcomes: a Systematic Review and Meta-analysis

Neil Thayamballi #  1   2 , Sara Habiba #  1   2 , Ouahiba Laribi  1 , Keita Ebisu  3
Affiliations
Meta-Analysis

Impact of Maternal Demographic and Socioeconomic Factors on the Association Between Particulate Matter and Adverse Birth Outcomes: a Systematic Review and Meta-analysis

Neil Thayamballi et al. J Racial Ethn Health Disparities. 2021 Jun.

Abstract

Background: Numerous studies conducted in the United States found associations between prenatal exposure to particulate matter (PM) and adverse birth outcomes, and some studies identified vulnerable populations, including certain racial/ethnic groups and people with low-socioeconomic status. However, their findings are not always consistent. In this review, we compared the risk of adverse birth outcomes due to PM exposures among subpopulations and investigated whether any particular population is more vulnerable.

Methods: We selected U.S. studies examining associations between PM exposure during pregnancy and birth outcomes that included results for effect modification by race/ethnicity and/or maternal education. We summarized the findings for various sizes of PM and birth outcomes. Meta-analysis was conducted to quantify vulnerable race/ethnicity for the association between fine PM (PM2.5) and birthweight.

Results: In total, 19 studies were assessed, and PM-related risks of adverse birth outcomes, particularly those related to fetal growth, likely differ across subpopulations. A meta-analysis from five studies showed that a 10 μg/m3 increase of PM2.5 during the full-gestation reduced birthweight by 21.9 g (95% confidence interval 11.7, 32.0), 15.7 g (10.1, 21.4), 9.3 g (2.7, 15.8), and 5.8 g (- 9.0, 20.7) for Black, White, Hispanic, and Asian mothers, respectively.

Conclusion: Our review indicated that Black mothers and mothers with low educational attainment are more vulnerable subpopulations. More investigation is needed for effect modification by other maternal factors, such as household income. Characterizing and quantifying vulnerable subpopulations are essential for addressing environmental justice since it can help regulatory agencies allocate resources and design policy interventions.

Keywords: Birth outcome; Environmental justice; Particulate matter; Vulnerable population.

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References

    1. Ebisu K, Malig B, Hasheminassab S, Sioutas C. Age-specific seasonal associations between acute exposure to PM2. 5 sources and cardiorespiratory hospital admissions in California. Atmos Environ. 2019;218:117029. - DOI
    1. Atkinson RW, Kang S, Anderson HR, Mills IC, Walton HA. Epidemiological time series studies of PM2.5 and daily mortality and hospital admissions: a systematic review and meta-analysis. Thorax. 2014;69(7):660–5. https://doi.org/10.1136/thoraxjnl-2013-204492 . - DOI - PubMed - PMC
    1. DeFranco E, Hall E, Hossain M, Chen A, Haynes EN, Jones D, et al. Air pollution and stillbirth risk: exposure to airborne particulate matter during pregnancy is associated with fetal death. PLoS One. 2015;10(3):e0120594. https://doi.org/10.1371/journal.pone.0120594 . - DOI - PubMed - PMC
    1. Girguis MS, Strickland MJ, Hu X, Liu Y, Bartell SM, Vieira VM. Maternal exposure to traffic-related air pollution and birth defects in Massachusetts. Environ Res. 2016;146:1–9. https://doi.org/10.1016/j.envres.2015.12.010 . - DOI - PubMed
    1. Basu R, Harris M, Sie L, Malig B, Broadwin R, Green R. Effects of fine particulate matter and its constituents on low birth weight among full-term infants in California. Environ Res. 2014;128:42–51. https://doi.org/10.1016/j.envres.2013.10.008 . - DOI - PubMed

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