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Clinical Trial
. 1988 May;26(5):1047-9.
doi: 10.1128/jcm.26.5.1047-1049.1988.

Test-of-cure stool cultures for traveler's diarrhea

C D Ericsson  1 , H L DuPont, J J Mathewson, P C Johnson, F J de la Cabada, J A Bitsura
Affiliations
Clinical Trial

Test-of-cure stool cultures for traveler's diarrhea

C D Ericsson et al. J Clin Microbiol. 1988 May.

Abstract

Whether enteropathogens were eradicated or persisted in test-of-cure stool cultures from 251 patients with traveler's diarrhea, the durations of diarrhea were similar within the antimicrobial agent-treated (32 versus 33 h) and placebo-treated (82 versus 96 h) groups. Routine test-of-cure stool cultures can be useful for evaluating treatment failures and for assessing asymptomatic carriage of enteropathogens after treatment, but they are not mandated in the design of placebo-controlled antimicrobial treatment trials in traveler's diarrhea when the focus of the trial is clinical efficacy.

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References

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