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Case Reports
. 2020 Aug 19:13:587-590.
doi: 10.2147/CCID.S260534. eCollection 2020.

Erosive Adenomatosis of the Nipple: A Clinical Diagnostic Challenge

Shuni Ying  1 , Hong Fang  1 , Jianjun Qiao  1
Affiliations
Case Reports

Erosive Adenomatosis of the Nipple: A Clinical Diagnostic Challenge

Shuni Ying et al. Clin Cosmet Investig Dermatol. .

Abstract

Erosive adenomatosis of the nipple (EAN) is a rare benign neoplasm of the nipple. The entity is generally characterized by erosion, serous discharge (serous and/or sanguineous), nodularity, swelling, itching and erythema of the nipple. It may be confused with mammary Paget's disease of the nipple and obtain over-treatment. We reported a patient with typical clinical and histopathological features. Clinicians should consider EAN as one of the differential diagnosis in patients with erosions on the nipple.

Keywords: adenoma; breast neoplasm; erosive adenomatosis of the nipple; histopathology; surgical excision.

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Conflict of interest statement

The authors report no conflicts of interest in this work.

Figures

Figure 1
Figure 1
Photograph of the lesion on the left nipple. Erosion and crust on the left nipple.
Figure 2
Figure 2
(A and B) Histopathology reveals ductal differentiation. (Hematoxylin-eosin stain, Original magnification×40 (A); Original magnification×200 (B)). The luminal epithelial cells were positive for (C) CK5/6 stain. (Immunohistochemistry, original magnification×100). The out-layer myoepithelial cells were positive for (D) SMA and (E) p63 stains. (Immunohistochemistry, original magnification×100).
See this image and copyright information in PMC

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