Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2020 Aug 24:14:2427-2440.
doi: 10.2147/OPTH.S270708. eCollection 2020.

Intraoperative Optical Coherence Tomography Guided Ocular Surgeries: Critical Analysis of Clinical Role and Future Perspectives

Amar Pujari #  1 , Divya Agarwal #  1 , Rohan Chawla  1 , Atul Kumar  1 , Namrata Sharma  1
Affiliations
Review

Intraoperative Optical Coherence Tomography Guided Ocular Surgeries: Critical Analysis of Clinical Role and Future Perspectives

Amar Pujari et al. Clin Ophthalmol. .

Abstract

Intraoperative imaging of ocular tissues for diagnostic and therapeutic applications has gained immense admiration in recent years. The real time cross-sectional imaging, as well as three and four dimensional reconstruction abilities of intraoperative optical coherence tomography (iOCT), has enhanced our knowledge on many fronts in surgical maneuvers. In this review, we discuss the iOCT discovered constructive knowledge in the cornea, cataract, refractive, glaucoma, pediatric ocular, and various retinal conditions. The practical utility with decision modifying aspects along the specified ocular tissues and with respect to specific ocular entities have been narrated. Moreover, limitations and future directions have also been emphasized to make ophthalmic care more comprehensive in the future.

Keywords: hand-held optical coherence tomography and intraoperative microscope integrated optical coherence tomography; iOCT; intraoperative optical coherence tomography.

PubMed Disclaimer

Conflict of interest statement

The authors report no conflicts of interest for this work.

Figures

Figure 1
Figure 1
iOCT guided depth resolved detailed augmentation of air injection procedure with graded tissue dissection during big bubble Deep Anterior Lamellar Keratoplasty.
Figure 2
Figure 2
Full thickness corneal perforation with uveal tissue prolapse is better delineated under iOCT. Iris reposition, depth guided suturing and optimal anterior chamber formation in the presence of hazy cornea are well ensured on iOCT.
Figure 3
Figure 3
In presence of hazy cornea orientation DMEK scroll can also be better ensured with iOCT.
Figure 4
Figure 4
Intraoperatively vaulting and other parameters during phakic IOL surgery can be monitored in real time with iOCT.
Figure 5
Figure 5
A posterior polar cataract imaged on iOCT prior to initiation of surgery showing an intact posterior capsule.
Figure 6
Figure 6
During rectus muscle recession surgery the thin sclera was imaged using iOCT. The approximate thickness guided suture passage helped in preventing scleral complications with real time information.
Figure 7
Figure 7
iOCT helped in the visualization of a well-configured ILM flap which is covering the entire defect in a case of large full-thickness macular hole. Intricate details of retinal architecture can also be studied.
Figure 8
Figure 8
iOCT providing details in detecting the precise location of residual foveal traction and possible occurrence of a full-thickness macular hole if any. This is useful while performing center sparing ILM peeling in cases of myopic traction maculopathy.
See this image and copyright information in PMC

References

    1. Huang D, Swanson EA, Lin CP, et al. Optical coherence tomography. Science. 1991;254(5035):1178‐1181. doi:10.1126/science.1957169 - DOI - PMC - PubMed
    1. Titiyal JS, Kaur M, Falera R. Intraoperative optical coherence tomography in anterior segment surgeries. Indian J Ophthalmol. 2017;65(2):116–121. doi:10.4103/ijo.IJO_868_16 - DOI - PMC - PubMed
    1. Hahn P, Migacz J, O’Connell R, et al. The use of optical coherence tomography in intraoperative ophthalmic imaging. Ophthalmic Surg Lasers Imaging. 2011;42(4):S85–S94. doi:10.3928/15428877-20110627-08 - DOI - PMC - PubMed
    1. Augustin AJ. Intraoperative optical coherence tomography - an overview of current clinical data for the application in the anterior and posterior segments. Klin Monatsbl Augenheilkd. 2018;235(7):820–829. doi:10.1055/s-0042-122710 - DOI - PubMed
    1. Khan M, Ehlers JP. Clinical utility of intraoperative optical coherence tomography. Curr Opin Ophthalmol. 2016;27(3):201–209. doi:10.1097/ICU.0000000000000258 - DOI - PMC - PubMed

LinkOut - more resources