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Review
. 2020 Sep;29(3):149-155.
doi: 10.1055/s-0040-1710075. Epub 2020 May 14.

The Role of Lower Extremity Amputation in Chronic Limb-Threatening Ischemia

Affiliations
Review

The Role of Lower Extremity Amputation in Chronic Limb-Threatening Ischemia

Tanner I Kim et al. Int J Angiol. 2020 Sep.

Abstract

Chronic limb-threatening ischemia (CLTI) is a severe form of peripheral artery disease associated with high rates of limb loss. The primary goal of treatment in CLTI is limb salvage via revascularization. Multidisciplinary teams provide improved care for those with CLTI and lead to improved limb salvage rates. Not all patients are candidates for revascularization, and a subset will require major amputation. This article highlights the role of amputations in the management of CLTI, and describes the patients who should be offered primary amputation.

Keywords: amputation; artery; chronic limb-threatening ischemia; end-stage renal disease; peripheral artery disease; risk factors.

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Conflict of interest statement

Conflict of Interest C.M. is a consultant for Bard, Cook, Cardinal Health, Boston Scientific, and Medtronic. B.E.S. is a consultant for Hypermed.

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