Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2020 Jul 29:15:e11.
doi: 10.15420/icr.2020.07. eCollection 2020 Apr.

Intraventricular Conduction Disturbances After Transcatheter Aortic Valve Implantation

Affiliations
Review

Intraventricular Conduction Disturbances After Transcatheter Aortic Valve Implantation

Shu-I Lin et al. Interv Cardiol. .

Erratum in

Abstract

Despite significant improvements in transcatheter aortic valve implantation (TAVI) outcomes, periprocedural conduction disturbances, such as new-onset left bundle branch block (LBBB) and new pacemaker implantation (PMI), remain relatively frequent concerns. The development of periprocedural conduction disturbances can be explained by the proximity between the aortic valve and the conduction system. Although prior studies reported heterogeneity in PMI rates after TAVI, current evidence supports the potentially deleterious consequence of LBBB and PMI, and several predisposing factors have been reported. Therefore, new strategies to avoid conduction disturbances and to improve their management are required, particularly with the current trend to expand TAVI to a low-risk population.

Keywords: Transcatheter aortic valve implantation; conduction abnormality; left bundle branch block; pacemaker implantation.

PubMed Disclaimer

Conflict of interest statement

Disclosure: MM has been a consultant for Japan Lifeline. APT is supported by Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES), Brazil (Finance Code 001). RP has received consulting fees from Medtronic and has minor equity in Centerline Biomedical. FM has received grant and/or research support from Abbott, Medtronic, Edwards Lifesciences, Biotronik, Boston Scientific Corporation, NVT and Terumo; receives consulting fees and honoraria from Abbott, Medtronic, Edwards Lifesciences, SwissVortex, Perifect, Xeltis, Transseptal Solutions, Cardiovalve and Magenta; has royalty income or intellectual property rights from Edwards Lifesciences; and is a shareholder of Cardiovalve, Cardiogard, Magenta, SwissVortex, Transseptal Solutions, 4Tech and Perifect. MT is a consultant for Abbott Vascular, Boston Scientific, 4tech and CoreMedic; and has received speaker honoraria from Edwards Lifesciences. All other authors have no conflicts of interest to declare.

Figures

Figure 1:
Figure 1:. Anatomical Relationships Between the Aortic Cuspids, Membrane Septum and Conduction System
Figure 2:
Figure 2:. ‘Cusp Overlap’ Technique With the Evolut System
Figure 3:
Figure 3:. High Implantation Technique for the SAPIEN 3

References

    1. Baumgartner H, Falk V, Bax JJ et al. 2017 ESC/EACTS guidelines for the management of valvular heart disease. Eur Heart J. 2017;38:2739–91. doi: 10.1093/eurheartj/ehx391. - DOI - PubMed
    1. Mack MJ, Leon MB, Thourani VH et al. Transcatheter aortic-valve replacement with a balloon-expandable valve in low-risk patients. N Engl J Med. 2019;380:1695–705. doi: 10.1056/NEJMoa1814052. - DOI - PubMed
    1. Popma JJ, Deeb GM, Yakubov SJ et al. Transcatheter aortic-valve replacement with a self-expanding valve in low-risk patients. N Engl J Med. 2019;380:1706–15. doi: 10.1056/NEJMoa1816885. - DOI - PubMed
    1. De Torres-Alba F, Kaleschke G, Diller GP et al. Changes in the pacemaker rate after transition from Edwards SAPIEN XT to SAPIEN 3 transcatheter aortic valve implantation: the critical role of valve implantation height. JACC Cardiovasc Interv. 2016;9:805–13. doi: 10.1016/j.jcin.2015.12.023. - DOI - PubMed
    1. Barbanti M, Gulino S, Costa G, Tamburino C. Pathophysiology, incidence and predictors of conduction disturbances during transcatheter aortic valve implantation. Expert Rev Med Devices. 2017;14:135–47. doi: 10.1080/17434440.2017.1282819. - DOI - PubMed

LinkOut - more resources