Wait and see approach for dialysis in acute kidney injury
- PMID: 32908301
- PMCID: PMC9128621
- DOI: 10.1038/s41581-020-00351-w
Wait and see approach for dialysis in acute kidney injury
Abstract
Timing of dialysis initiation in critically ill patients is controversial. The STARRT-A KI trial reports that an accelerated initiation strategy did not improve 90- day survival and increased dialysis dependency compared with a standard approach in which patients had greater fluid accumulation and metabolic complications at initiation but 38% avoided dialysis.
References
-
- Wald R et al. Changing incidence and outcomes following dialysis-requiring acute kidney injury among critically ill adults: a population-based cohort study. Am. J. Kidney Dis. 65, 870–877 (2015). - PubMed
-
- Zarbock A et al. Effect of early versus delayed initiation of renal replacement therapy on mortality in critically ill patients with acute kidney injury: the ELAIN randomized clinical trial. JAMA 315, 2190–2199 (2016). - PubMed
-
- Gaudry S et al. Initiation strategies for renalreplacement therapy in the intensive care unit. N. Engl. J. Med. 375, 122–133 (2016) - PubMed
-
- Barbar SD et al. Timing of renal-replacement therapy in patients with acute kidney injury and sepsis. N. Engl. J. Med. 379, 1431–1442 (2018). - PubMed
-
- Investigators S-A et al. Timing of initiation of renalreplacement therapy in acute kidney injury. N. Engl. J. Med. 383, 240–251 (2020). - PubMed
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