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. 2020 Jun 26;12(Suppl 1):8682.
doi: 10.4081/or.2020.8682. eCollection 2020 Jun 29.

The role of adipose derived stem cells in the treatment of rotator cuff tears: from basic science to clinical application

Fabrizio Mocini  1 , Andrea Stefano Monteleone  1 , Piero Piazza  1 , Valentina Cardona  1 , Valeria Vismara  1 , Piermarco Messinese  1 , Vincenzo Campana  1 , Giuseppe Sircana  1 , Giulio Maccauro  1 , Maristella Francesca Saccomanno  1
Affiliations

The role of adipose derived stem cells in the treatment of rotator cuff tears: from basic science to clinical application

Fabrizio Mocini et al. Orthop Rev (Pavia). .

Abstract

Over the last decade, regenerative medicine has become increasingly popular throughout the scientific community. The poor healing capacity at the tendon-bone interface makes the rotator cuff an appealing target for biologic agents. Adipose derived stem cells are mesenchymal cells with the capacity for self-renewal and multipotential differentiation. They have been recently proposed, both in isolation and as adjuvants to existing surgical therapies, for the treatment of rotator cuff tears. Several studies have been carried out in this research field, starting from the biological characteristics of adipose derived stem cells, their preparation and culture, up to the application in the experimental field on animal models and on humans. The purpose of this study was to provide a state of the art about the current basic science and clinical literature for the effectiveness of adipose derived stem cells in the treatment of rotator cuff tears.

Keywords: Adipose derived stem cells; Regenerative medicine; Rotator Cuff Tears.

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Conflict of interest statement

Conflict of interest: the authors declare no potential conflict of interest.

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