Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Jun 26;12(Suppl 1):8685.
doi: 10.4081/or.2020.8685. eCollection 2020 Jun 29.

Symptomatic vertebral hemangioma during pregnancy period: A case series and systematic literature review

Domenico Alessandro Santagada  1 , Andrea Perna  1 , Maria Concetta Meluzio  1 , Gianluca Ciolli  1 , Luca Proietti  1 , Francesco Ciro Tamburrelli  1
Affiliations

Symptomatic vertebral hemangioma during pregnancy period: A case series and systematic literature review

Domenico Alessandro Santagada et al. Orthop Rev (Pavia). .

Abstract

Vertebral Hemangioma (VH) is a benign tumor usually symptomless and discovered incidentally. Pregnancy, because of several hormonal and physiologic changes, is a recognized risk factor coinciding with the development of a rapid onset of neurological symptoms in patients affected by VH. In the Literature, sporadic cases of neurological symptoms have been described, which occurred during pregnancy, but only rarely the onset of symptoms was reported after pregnancy and childbirth. Usually surgical treatment is reserved for severe cases with rapid onset of neurological symptoms. However, the use of conservative treatments is still a topic of debate In the present study, we report a series of patients affected by VH become symptomatic during or after pregnancy along with a systematic review of the Literature.

Keywords: paraparesis; pregnancy; spine; spine tumors; vertebral hemangioma.

PubMed Disclaimer

Conflict of interest statement

Conflict of interest: the authors declare no potential conflict of interest.

Figures

Figure 1.
Figure 1.
PRISMA Flow-chart.
Figure 2.
Figure 2.
a-c) TC images showing complete collapse of L1with back wall protruding into the spinal canal, in figure c there was bone changes extended to both the pedicles (honey comb pattern). d, MR images showing vertebral body collapse and cord compression.
Figure 3.
Figure 3.
Radiograph at 3 month of follow-up.
Figure 4.
Figure 4.
a-c) TC images showing compression fracture of L1body. d,e) Radiograph at 3 month of follow-up.
Figure 5.
Figure 5.
a) MR images showing T2 vertebral body lesion with epidural invasion and cord compression. b) Fluoroscopic image obtained during embolization. c) MR images at 3 months of follow-up showing a reduction of the lesion in T2 and free-compression spinal cord.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

References

    1. Demirkale İ, De Iure F, Terzi S, Gasbarrini A. Aggressive hemangioma of the spine in a pregnant female: a case report and literature review. Eklem Hastalik Cerrahisi 2016;27:46-50. - PubMed
    1. Moles A, Hamel O, Perret C, et al. Symptomatic vertebral hemangiomas during pregnancy. J Neurosurg Spine 2014;20:585-91. - PubMed
    1. Guthekelch AN. Haemangiomas involving the spinal epidural space. J Neurol Neurosurg Psychiatry 1948;11:199-210. - PMC - PubMed
    1. Lam RL, Roulhac GE, Erwin HJ. Hemangioma of the spinal canal and pregnancy. J Neurosurg 1951;8:668-71. - PubMed
    1. Askenasy H, Behmoaram A. Neurological manifestations in haemangioma of the vertebrae. J Neurol Neurosurg Psychiatry 1957;20:276-84. - PMC - PubMed