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. 2020 Jun 26;12(Suppl 1):8685.
doi: 10.4081/or.2020.8685. eCollection 2020 Jun 29.

Symptomatic vertebral hemangioma during pregnancy period: A case series and systematic literature review

Domenico Alessandro Santagada  1 , Andrea Perna  1 , Maria Concetta Meluzio  1 , Gianluca Ciolli  1 , Luca Proietti  1 , Francesco Ciro Tamburrelli  1
Affiliations

Symptomatic vertebral hemangioma during pregnancy period: A case series and systematic literature review

Domenico Alessandro Santagada et al. Orthop Rev (Pavia). .

Abstract

Vertebral Hemangioma (VH) is a benign tumor usually symptomless and discovered incidentally. Pregnancy, because of several hormonal and physiologic changes, is a recognized risk factor coinciding with the development of a rapid onset of neurological symptoms in patients affected by VH. In the Literature, sporadic cases of neurological symptoms have been described, which occurred during pregnancy, but only rarely the onset of symptoms was reported after pregnancy and childbirth. Usually surgical treatment is reserved for severe cases with rapid onset of neurological symptoms. However, the use of conservative treatments is still a topic of debate In the present study, we report a series of patients affected by VH become symptomatic during or after pregnancy along with a systematic review of the Literature.

Keywords: paraparesis; pregnancy; spine; spine tumors; vertebral hemangioma.

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Conflict of interest statement

Conflict of interest: the authors declare no potential conflict of interest.

Figures

Figure 1.
Figure 1.
PRISMA Flow-chart.
Figure 2.
Figure 2.
a-c) TC images showing complete collapse of L1with back wall protruding into the spinal canal, in figure c there was bone changes extended to both the pedicles (honey comb pattern). d, MR images showing vertebral body collapse and cord compression.
Figure 3.
Figure 3.
Radiograph at 3 month of follow-up.
Figure 4.
Figure 4.
a-c) TC images showing compression fracture of L1body. d,e) Radiograph at 3 month of follow-up.
Figure 5.
Figure 5.
a) MR images showing T2 vertebral body lesion with epidural invasion and cord compression. b) Fluoroscopic image obtained during embolization. c) MR images at 3 months of follow-up showing a reduction of the lesion in T2 and free-compression spinal cord.
See this image and copyright information in PMC

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