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Review
. 2021 Mar;26(2):347-353.
doi: 10.1007/s10741-020-10026-0. Epub 2020 Sep 10.

Hospitalizations in adult patients with congenital heart disease: an emerging challenge

Affiliations
Review

Hospitalizations in adult patients with congenital heart disease: an emerging challenge

Despoina Ntiloudi et al. Heart Fail Rev. 2021 Mar.

Abstract

The vast majority of patients with congenital heart disease (CHD) survive into adulthood, but many face lifelong complications, which often result in a hospital admission. The increasing number of hospitalizations in adults with CHD (ACHD) poses a significant challenge for healthcare systems globally, especially as heart failure (HF) is becoming increasingly common in this population and is the leading cause of morbidity and mortality. Besides HF, other major contributors to this increase in admission volume are hospitalizations related to mild lesions, comorbidities and pregnancies. Ιn-hospital mortality ranges between 0.8 and 6.1%, while hospitalizations related to HF predict medium-term mortality in ACHD population. Understanding the predictors of hospitalization and in-hospital mortality is, therefore, important for ACHD healthcare providers, who should identify patients at risk that require escalation of treatment and/or close monitoring. This article reviews the available literature on hospitalization patterns in ACHD patients, with a focus on HF-related hospital admissions and specific diagnostic subgroups.

Keywords: Adult congenital heart disease; Heart failure; Hospitalization.

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References

    1. Ntiloudi D, Giannakoulas G, Parcharidou D, Panagiotidis T, Gatzoulis MA, Karvounis H (2016) Adult congenital heart disease: a paradigm of epidemiological change. Int J Cardiol 218:269–274 - DOI
    1. Afilalo J, Therrien J, Pilote L, Ionescu-Ittu R, Martucci G, Marelli AJ (2011) Geriatric congenital heart disease: burden of disease and predictors of mortality. J Am Coll Cardiol 58:1509–1515 - DOI
    1. Tutarel O, Kempny A, Alonso-Gonzalez R, Jabbour R, Li W, Uebing A, Dimopoulos K, Swan L, Gatzoulis MA, Diller GP (2014) Congenital heart disease beyond the age of 60: emergence of a new population with high resource utilization, high morbidity, and high mortality. Eur Heart J 35:725–732 - DOI
    1. Giannakoulas G, Vasiliadis K, Frogoudaki A, Ntellos C, Tzifa A, Brili S, Manginas A, Papaphylactou M, Parcharidou D, Kampouridis N, Pitsis A, Chamaidi A, Kolios M, Papadopoulos G, Douras A, Davlouros P, Ntiloudi D, Karvounis H, Kalangos A, Tsioufis C, Rammos S (2017) Adult congenital heart disease in Greece: preliminary data from the CHALLENGE registry. Int J Cardiol 245:109–113 - DOI
    1. Ntiloudi D, Zanos S, Gatzoulis MA, Karvounis H, Giannakoulas G (2019) How to evaluate patients with congenital heart disease-related pulmonary arterial hypertension. Expert Rev Cardiovasc Ther 17:11–18 - DOI

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