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. 2020 Oct;17(10):1092-1094.
doi: 10.1038/s41423-020-00522-6. Epub 2020 Sep 11.

Sepsis-associated severe interleukin-6 storm in critical coronavirus disease 2019

Lan Huang #  1 , Xuan Zhao #  2 , Yu Qi #  3 , Hong Li  2 , Guanchao Ye  3 , Yafei Liu  3 , Yi Zhang  4 , Jianjun Gou  5
Affiliations

Sepsis-associated severe interleukin-6 storm in critical coronavirus disease 2019

Lan Huang et al. Cell Mol Immunol. 2020 Oct.
No abstract available

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Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
Severe storms of plasma IL-6 were strongly associated with the presence of sepsis and a fatal outcome in 29 severe or critical patients with COVID-19. Comparison of maximal plasma IL-6 levels based on disease severity (a), status of sepsis (b), PCT value (c), and clinical outcome (d). The data are presented as the means + SDs. The Mann–Whitney U test was applied to assess the statistical significance of the differences between two groups. e The prognostic values of maximal plasma cytokines were evaluated by ROC analysis
See this image and copyright information in PMC

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