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Case Reports
. 2020 Dec;26(6):964-966.
doi: 10.1007/s13365-020-00908-2. Epub 2020 Sep 11.

Autonomic dysfunction heralding acute motor axonal neuropathy in COVID-19

Ritwik Ghosh  1 , Dipayan Roy  2 , Samya Sengupta  3 , Julián Benito-León  4   5   6
Affiliations
Case Reports

Autonomic dysfunction heralding acute motor axonal neuropathy in COVID-19

Ritwik Ghosh et al. J Neurovirol. 2020 Dec.

Abstract

Albeit primarily a disease of respiratory tract, the 2019 coronavirus infectious disease (COVID-19) has been found to have causal association with a plethora of neurological and neuropsychological effects. However, the pathogenesis of COVID-19-induced neurological manifestations is still in its infancy. Autonomic dysfunction preceding acute motor axonal neuropathy (AMAN) has not been yet associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. We herein report one patient who developed acute onset dysautonomia heralding AMAN during SARS-CoV-2 infection.

Keywords: Acute motor axonal neuropathy; Autonomic dysfunction; COVID-19; SARS-CoV-2.

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Conflict of interest statement

R. Ghosh, D. Ray, and S. Sengupta report no relevant disclosures. J. Benito-León is supported by the National Institutes of Health, Bethesda, MD, USA (NINDS #R01 NS39422), European Commission (grant ICT-2011-287739, NeuroTREMOR), the Ministry of Economy and Competitiveness (grant RTC-2015-3967-1, NetMD—platform for the tracking of movement disorder), and the Spanish Health Research Agency (grant FIS PI12/01602 and grant FIS PI16/00451).

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