Review
doi: 10.1007/978-3-030-46227-7_11.
The Immune System and Pathogenesis of Melanoma and Non-melanoma Skin Cancer
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- PMID: 32918221
- DOI: 10.1007/978-3-030-46227-7_11
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Review
The Immune System and Pathogenesis of Melanoma and Non-melanoma Skin Cancer
Adv Exp Med Biol.
2020.
Abstract
Tumor development is the result of genetic derangement and the inability to prevent unfettered proliferation. Genetic derangements leading to tumorigenesis are variable, but the immune system plays a critical role in tumor development, prevention, and production. In this chapter, we will discuss the importance of the immune system as it relates to the development of skin cancer-both melanoma and non-melanoma skin cancers (NMSC).
Keywords: Immunopathogenesis; Immunosuppression; Immunotherapy; Melanoma; Non-melanoma skin cancer; TVEC.
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