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Review
. 2020 Sep;43(9):900-919.
doi: 10.1007/s12272-020-01266-7. Epub 2020 Sep 12.

Applications of deep eutectic solvents to quantitative analyses of pharmaceuticals and pesticides in various matrices: a brief review

Jeongmi Lee  1 , Hireem Kim  2 , Seulgi Kang  2 , Namwook Baik  2 , Inseon Hwang  2 , Doo Soo Chung  3
Affiliations
Review

Applications of deep eutectic solvents to quantitative analyses of pharmaceuticals and pesticides in various matrices: a brief review

Jeongmi Lee et al. Arch Pharm Res. 2020 Sep.

Abstract

Pharmaceuticals and pesticides are important analytes of interest in clinical, environmental, and food analyses for ensuring public health. Sample pretreatment steps are often prerequisites for the quantitative analysis of these compounds, which are generally present in low concentrations in samples with complex matrices. In compliance with the current trend towards green analytical chemistry, the replacement of conventional toxic organic solvents with ecofriendly and safe solvents has been pursued in developing sample pretreatment methods. Subsequent to several reports in 2017, deep eutectic solvents (DESs) have been increasingly applied as desirable alternative solvents in numerous types of sample pretreatment methods for the analysis of pharmaceuticals and pesticides. The present review summarizes analytical methods involving DESs as extraction solvents and as the reaction media or functional materials for preparing adsorbents to quantify pharmaceuticals and pesticides in various matrices.

Keywords: Deep eutectic solvents; Green analytical chemistry; Pesticides; Pharmaceuticals; Sample pretreatment.

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