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. 2021 Jul;27(5):1300-1312.
doi: 10.1111/odi.13641. Epub 2020 Oct 6.

Tooth extraction without discontinuation of oral antithrombotic treatment: A prospective study

Roberto Pippi  1 , Maria Giulia Scorsolini  1 , Luca Luigetti  1 , Alessandra Pietrantoni  1 , Arturo Cafolla  2
Affiliations

Tooth extraction without discontinuation of oral antithrombotic treatment: A prospective study

Roberto Pippi et al. Oral Dis. 2021 Jul.

Abstract

Objective: To identify which variable, among those related to surgeries, to patients, or to antithrombotic treatments, could be considered as a bleeding indicator, and to analyze effectiveness of the local hemostatic protocols used, incidence of bleeding and healing index, depending on the number of extracted teeth, and patient antithrombotic treatment.

Methods: Patients who underwent tooth extractions without interruption or reduction of antithrombotic treatment were prospectively followed. The exact two-tailed Fisher test was used to investigate the relationship between presence/absence of bleeding and type of hemostatic material. The effect of variables on the probability of bleeding and healing index was assessed by means of a multivariate logistic regression.

Results: Two hundred and fifty-four procedures were analyzed. The incidence of bleeding was 15.75%. Severe bleeding occurred in only 6 patients (2.34%). The number of involved dental quadrants and pre-surgical antibiotic treatments were found to be positively related with bleeding. The use of vasoconstrictors during surgery resulted in a reduction of healing index scores.

Conclusions: Tooth extractions in patients on antithrombotic treatment were found to be free from significant bleeding although the involvement of more than 1 quadrant in the same procedure should be avoided.

Keywords: Fisher test; bleeding; healing; multivariate analysis.

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References

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