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Review
. 2020 Sep 15;14(5):560-570.
doi: 10.5009/gnl20154.

Guidelines for Nonvariceal Upper Gastrointestinal Bleeding

Joon Sung Kim  1 , Byung-Wook Kim  1 , Do Hoon Kim  2 , Chan Hyuk Park  3 , Hyuk Lee  4 , Moon Kyung Joo  5 , Da Hyun Jung  6 , Jun-Won Chung  7 , Hyuk Soon Choi  5 , Gwang Ho Baik  8 , Jeong Hoon Lee  2 , Kyo Young Song  9 , Saebeom Hur  10
Affiliations
Review

Guidelines for Nonvariceal Upper Gastrointestinal Bleeding

Joon Sung Kim et al. Gut Liver. .

Abstract

Nonvariceal upper gastrointestinal bleeding (NVUGIB) refers to bleeding that develops in the gastrointestinal tract proximal to the ligament of Treitz. NVUGIB requires hospitalization and is associated with significant morbidity and mortality. Although European and Asian-Pacific guidelines have been published, there have been no previous guidelines regarding management of NVUGIB in Korea. Korea has a high prevalence of Helicobacter pylori infections, and patients have easy accessibility to endoscopy. Therefore, we believe that guidelines regarding management of NVUGIB in Korea are essential. The Korean Society of Gastroenterology reviewed the recent evidence and recommends practical management guidelines on NVUGIB in Korea.

Keywords: Antithrombotics; Guideline; Nonsteroidal anti-inflammatory drug; Nonvariceal upper gastrointestinal bleeding.

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Conflict of interest statement

CONFLICTS OF INTEREST

No potential conflict of interest relevant to this article was reported.

References

    1. Laine L. Clinical practice: upper gastrointestinal bleeding due to a peptic ulcer. N Engl J Med. 2016;374:2367–2376. doi: 10.1056/NEJMcp1514257. - DOI - PubMed
    1. Laine L, Yang H, Chang SC, Datto C. Trends for incidence of hospitalization and death due to GI complications in the United States from 2001 to 2009. Am J Gastroenterol. 2012;107:1190–1195. doi: 10.1038/ajg.2012.168. - DOI - PubMed
    1. Quan S, Frolkis A, Milne K, et al. Upper-gastrointestinal bleeding secondary to peptic ulcer disease: incidence and outcomes. World J Gastroenterol. 2014;20:17568–17577. doi: 10.3748/wjg.v20.i46.17568. - DOI - PMC - PubMed
    1. Tielleman T, Bujanda D, Cryer B. Epidemiology and risk factors for upper gastrointestinal bleeding. Gastrointest Endosc Clin N Am. 2015;25:415–428. doi: 10.1016/j.giec.2015.02.010. - DOI - PubMed
    1. Gralnek IM, Dumonceau JM, Kuipers EJ, et al. Diagnosis and management of nonvariceal upper gastrointestinal hemorrhage: European Society of Gastrointestinal Endoscopy (ESGE) Guideline. Endoscopy. 2015;47:a1–a46. doi: 10.1055/s-0034-1393172. - DOI - PubMed