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Case Reports
. 2020 Sep 7;91(3):e2020081.
doi: 10.23750/abm.v91i3.9026.

Bone methabolic disorders in HIV positive patients: a case report

Angelo De Carli  1 , Edoardo Gaj  2 , Davide Desideri  3 , Marco Scrivano  4 , Gianluca Fedeli  5 , Antonio Pasquale Vadala  6
Affiliations
Case Reports

Bone methabolic disorders in HIV positive patients: a case report

Angelo De Carli et al. Acta Biomed. .

Abstract

Fractures in patients affected by HIV are more frequent than what is reported in patients with no retroviral diseases. Chronic infection with HIV likely contributes to increased systemic inflammation, which has been associated with increased rates of fracture. We report a case of a 56-year-old male (HIV + in treatment with Atripla) heavy worker, at the beginning affected by intra-articular proximal humerus fracture treated with endoprosthesis replacement and later by periprosthetic fracture treated with plate, screws and cerclages. Follow up was performed with clinical evaluation (ROM, VAS, Quick Dash, ASES, Simple shoulder test, UCLA Score, Constant score) and shoulder radiographs. Bone metabolism disorders in HIV patients lead to low BMD values, changes in bone turnover markers, and histomorphometric abnormalities, especially when HIV is present along with HCV or other hepatopathies. Additional therapy with bisphosphonate and Vitamin D should always be carried out when possible to prevent such types of orthopaedic complications.

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Conflict of interest statement

Each author declares that he or she has no commercial associations (e.g. consultancies, stock ownership, equity interest, patent/licensing arrangement etc.) that might pose a conflict of interest in connection with the submitted article

Figures

Fig. 1
Fig. 1
Proximal humerus fracture; AO Classification: 11C3.2
Fig. 2
Fig. 2
Periprosthetic fracture;
Fig. 3
Fig. 3
Osteosynthesis of the fracture with plate, screws and cerclages.
See this image and copyright information in PMC

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