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Review
. 2020 Oct-Nov;60(6):554-558.
doi: 10.1016/j.reval.2020.07.003. Epub 2020 Sep 6.

[Allergic immunotherapy in children and adolescents]

[Article in French]
F Amat  1 , A Labbé  2
Affiliations
Review

[Allergic immunotherapy in children and adolescents]

[Article in French]
F Amat et al. Rev Fr Allergol (2009). 2020 Oct-Nov.

Abstract
in English, French

Specific allergic immunotherapy requires repeated administration of allergens in order to induce clinical and immunological tolerance. This is the only therapy with an aetiological aim that modifies the course of the disease by ensuring remission after the interruption of the procedure. The prevention of new sensitizations by immunotherapy is still under discussion. In this review we will consider the main immunological mechanisms and indications for immunotherapy in children and adolescents.

L’immunothérapie spécifique allergénique nécessite l’administration répétée d’allergènes dans le but de provoquer une tolérance clinique et immunologique. C’est la seule thérapeutique à visée étiologique qui permet de modifier l’évolution de la maladie en assurant une rémission après l’interruption de la procédure. La prévention de nouvelles sensibilisations par l’immunothérapie reste discutée. Nous envisagerons dans cette revue les principaux mécanismes immunologiques et les indications de l’immunothérapie chez l’enfant et l’adolescent.

Keywords: Adolescent; Asthma; Children; Food allergy; Immunotherapy; Rhinitis.

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Figures

Fig. 1
Fig. 1
Mécanismes immunologiques.
Fig. 2
Fig. 2
Terminologie pour les tests de provocation par voie orale d’après Casale et al. .
See this image and copyright information in PMC

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