Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1988 Jun;64(2):201-5.

Characterization of the IgA receptor from human polymorphonuclear leucocytes

M Albrechtsen  1 , G R Yeaman, M A Kerr
Affiliations

Characterization of the IgA receptor from human polymorphonuclear leucocytes

M Albrechtsen et al. Immunology. 1988 Jun.

Abstract

Human polymorphonuclear leucocytes (PMNs) will phagocytose yeasts opsonized with specific affinity-purified human serum IgA. PMNs also bind to Sepharose beads coated with IgA or IgG, but not to beads coated with bovine serum albumin (BSA) or horseradish peroxidase (HRP). Binding to IgA-Sepharose stimulates the cells to release lysozyme. Affinity chromatography of 125I-labelled PMN membrane proteins on IgA-Sepharose results in isolation of a polypeptide of apparent 60,000 MW. The protein, which is not bound to IgG-Sepharose under the same conditions, appears as a diffuse band on SDS-PAGE, suggesting it is heavily glycosylated.

PubMed Disclaimer

References

    1. J Immunol Methods. 1986 Apr 17;88(2):171-3 - PubMed
    1. J Exp Med. 1986 Apr 1;163(4):826-36 - PubMed
    1. J Immunol. 1987 Jul 15;139(2):534-8 - PubMed
    1. Immunology. 1987 Jul;61(3):303-9 - PubMed
    1. Clin Exp Immunol. 1987 Apr;68(1):200-8 - PubMed

Publication types

MeSH terms

LinkOut - more resources