Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Multicenter Study
. 2021 Feb 1;116(2):420-421.
doi: 10.14309/ajg.0000000000000924.

Clinical Characteristics of COVID-19 Patients With Pre-existing Hepatitis B Virus Infection: A Multicenter Report

Qing He  1 , Guo Zhang  2 , Ye Gu  3 , Jitao Wang  4 , Qiyuan Tang  1 , Zicheng Jiang  5 , Chuxiao Shao  6 , Hongguang Zhang  7 , Zhenhuai Chen  8 , Baoyi Ma  9 , Dengxiang Liu  4 , Guanghang Xie  10 , Dan Xu  10 , Yifei Huang  10 , Haijun Zhang  10 , Mingkai Liang  10 , Huihong Huang  5 , Yan Wang  3 , Hongyan Liu  3 , Jie Yang  6 , Hongqiu Pan  7 , Shengqiang Zou  7 , Fujian Li  8 , Fang Wang  1 , Chuan Liu  10 , Wenjuan Wang  2 , Bin Xiong  11 , Xun Li  10 , Lei Liu  1 , Jianrong Yang  2 , Xiaolong Qi  10
Affiliations
Multicenter Study

Clinical Characteristics of COVID-19 Patients With Pre-existing Hepatitis B Virus Infection: A Multicenter Report

Qing He et al. Am J Gastroenterol. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

Guarantor of the article: Xiaolong Qi, MD.

Specific author contributions: Qing He, MD, Guo Zhang, MD, Ye Gu, MD, Jitao Wang, MD, Qiyuan Tang, MD, contributed equally to this work. Concept and design: X.Q. Acquisition of data: Q.H., G.Z., Y.G., Q.T., Z.J., C.S., H.Z., Z.C., B.M., D.L., H.H, Y.W., H.L., J.Y., H.P., S.Z., F.L., F.W., W.W., L.L., J.Y., B.X., and X.L. Analysis and interpretation of data: C.L., J.W., G.X., D.X., Y.H., H.Z., and M.L. Drafting of the manuscript: X.Q. and J.W. Critical revision of the manuscript: X.Q. All authors have contributed significantly to the work and fulfill the requirement of authorship.

Financial support: None to report.

Potential competing interests: None to report.

Figures

Figure 1.
Figure 1.
COVID-19 patients with pre-existing hepatitis B virus infection. (a) The distribution of 10 designed hospitals in 8 provincial administrative regions and the percentage of COVID-19 patients with pre-existing HBV infection. (b) The incidence of ICU admission or death in patients with or without HBV infection. HBV, hepatitis B virus; ICU, intensive care unit.
See this image and copyright information in PMC

Comment in

References

    1. Chen N, Zhou M, Dong X, et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: A descriptive study. Lancet 2020;395:507–13. - PMC - PubMed
    1. Zhang C, Shi L, Wang FS. Liver injury in COVID-19: Management and challenges. Lancet Gastroenterol Hepatol 2020;5:428–30. - PMC - PubMed
    1. Cooke GS, Andrieux-Meyer I, Applegate TL, et al. Accelerating the elimination of viral hepatitis: A Lancet Gastroenterology & Hepatology Commission. Lancet Gastroenterol Hepatol 2019;4:135–84. - PubMed
    1. Chan HL, Kwan AC, To KF, et al. Clinical significance of hepatic derangement in severe acute respiratory syndrome. World J Gastroenterol 2005;11:2148–53. - PMC - PubMed
    1. Wiegand SB, Jaroszewicz J, Potthoff A, et al. Dominance of hepatitis C virus (HCV) is associated with lower quantitative hepatitis B surface antigen and higher serum interferon-γ-induced protein 10 levels in HBV/HCV-coinfected patients. Clin Microbiol Infect 2015;21:710.e1–9. - PubMed