Human Leukocyte Antigen-DR Deficiency and Immunosuppression-Related End-Organ Failure in SARS-CoV2 Infection
- PMID: 32925313
- PMCID: PMC7386673
- DOI: 10.1213/ANE.0000000000005140
Human Leukocyte Antigen-DR Deficiency and Immunosuppression-Related End-Organ Failure in SARS-CoV2 Infection
Conflict of interest statement
The authors declare no conflicts of interest.
Figures

Comment on
-
Reduced Monocytic Human Leukocyte Antigen-DR Expression Indicates Immunosuppression in Critically Ill COVID-19 Patients.Anesth Analg. 2020 Oct;131(4):993-999. doi: 10.1213/ANE.0000000000005044. Anesth Analg. 2020. PMID: 32925314 Free PMC article.
Similar articles
-
Coronavirus Disease (Covid-19): What Are We Learning in a Country With High Mortality Rate?Front Immunol. 2020 May 28;11:1208. doi: 10.3389/fimmu.2020.01208. eCollection 2020. Front Immunol. 2020. PMID: 32574270 Free PMC article. No abstract available.
-
Response to 'Impact of immunosuppression on mortality in critically ill COVID-19 patients'.Br J Haematol. 2020 Nov;191(3):505-506. doi: 10.1111/bjh.17110. Epub 2020 Oct 26. Br J Haematol. 2020. PMID: 33103782 No abstract available.
-
Severe arterial thrombosis associated with Covid-19 infection.Thromb Res. 2020 Aug;192:75-77. doi: 10.1016/j.thromres.2020.05.025. Epub 2020 May 16. Thromb Res. 2020. PMID: 32425264 Free PMC article.
-
[Importance of corneal organ culture in donors with possible SARS-CoV-2 infections].Ophthalmologe. 2020 Jul;117(7):622-625. doi: 10.1007/s00347-020-01152-z. Ophthalmologe. 2020. PMID: 32556552 Free PMC article. Review. German.
-
Immunopathogenesis of COVID-19: Summary and Possible Interventions.Front Immunol. 2020 Sep 17;11:564925. doi: 10.3389/fimmu.2020.564925. eCollection 2020. Front Immunol. 2020. PMID: 33072103 Free PMC article. Review.
Cited by
-
Utility of Monocyte Expression of HLA-DR versus T Lymphocyte Frequency in the Assessment of COVID-19 Outcome.Int J Gen Med. 2022 May 19;15:5073-5087. doi: 10.2147/IJGM.S359690. eCollection 2022. Int J Gen Med. 2022. PMID: 35615469 Free PMC article.
-
Immunomodulatory effects of detoxification agents on dendritic cell populations in methamphetamine addiction.BMC Pharmacol Toxicol. 2025 May 19;26(1):106. doi: 10.1186/s40360-025-00943-x. BMC Pharmacol Toxicol. 2025. PMID: 40390118 Free PMC article.
-
Impact of Chronic HIV Infection on Acute Immune Responses to SARS-CoV-2.J Acquir Immune Defic Syndr. 2024 May 1;96(1):92-100. doi: 10.1097/QAI.0000000000003399. J Acquir Immune Defic Syndr. 2024. PMID: 38408318 Free PMC article.
-
COVID-19 Immunobiology: Lessons Learned, New Questions Arise.Front Immunol. 2021 Aug 26;12:719023. doi: 10.3389/fimmu.2021.719023. eCollection 2021. Front Immunol. 2021. PMID: 34512643 Free PMC article. Review.
-
The Role of Immunogenetics in COVID-19.Int J Mol Sci. 2021 Mar 5;22(5):2636. doi: 10.3390/ijms22052636. Int J Mol Sci. 2021. PMID: 33807915 Free PMC article. Review.
References
-
- Venet F, Tissot S, Debard AL, et al. Decreased monocyte human leukocyte antigen-DR expression after severe burn injury: correlation with severity and secondary septic shock. Crit Care Med. 2007;35:1910–1917. - PubMed
-
- Venet F, Rimmelé T, Monneret G. Management of sepsis-induced immunosuppression. Crit Care Clin. 2018;34:97–106. - PubMed
-
- Volk HD, Thieme M, Heym S, et al. Alterations in function and phenotype of monocytes from patients with septic disease—predictive value and new therapeutic strategies. Behring Inst Mitt. 1991:208–215. - PubMed
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
Miscellaneous