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Case Reports
. 2021 Jan;303(1):55-59.
doi: 10.1007/s00404-020-05778-x. Epub 2020 Sep 14.

Splenic pregnancy treated with transcatheter embolization and methotrexate

Antonis Makrigiannakis  1 , Maria Raissaki  2 , Thomas Vrekoussis  3 , Stefania Patramani  3 , Fanourios Makrygiannakis  3 , Nelli Kholcheva  2 , Dimitrios Tsetis  2
Affiliations
Case Reports

Splenic pregnancy treated with transcatheter embolization and methotrexate

Antonis Makrigiannakis et al. Arch Gynecol Obstet. 2021 Jan.

Abstract

Background: Primary splenic pregnancy is a rare entity, usually treated with splenectomy.

Case presentation and review of the literature: We report the first case of conservative management of splenic pregnancy with selective embolization and intramuscular methotrexate administration. Postoperative treatment was uneventful. We have further systematically reviewed the literature upon the treatment options in case of splenic pregnancy. It has been evident that most cases were treated with spleenectomy, especially in case of active hemorrhage. Spleen preservation is rarely achieved, only in cases of hemodynamically stable, uncomplicated patients.

Conclusion: Splenic selective embolization could be a treatment option in case of uncomplicated splenic pregnancy with the benefit of splenic preservation.

Keywords: Ectopic pregnancy; Embolization; Splenic pregnancy.

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References

    1. Bouyer J, Coste J, Fernandez H, Pouly JL, Job-Spira N (2002) Sites of ectopic pregnancy: a 10 year population-based study of 1800 cases. Human Reprod (Oxf, Engl) 17(12):3224–3230 - DOI
    1. Poole A, Haas D, Magann EF (2012) Early abdominal ectopic pregnancies: a systematic review of the literature. Gynecol Obstet Invest 74(4):249–260. https://doi.org/10.1159/000342997 - DOI - PubMed
    1. Zhang Y, Kang D, Zhang B, Yang L, Fan Z (2016) Ectopic pregnancy causing splenic rupture. Am J Emerg Med 34(6):1184.e1181–1182. https://doi.org/10.1016/j.ajem.2015.11.011 - DOI
    1. Studdiford W (1942) Primary peritoneal pregnancy. Am J Obstet Gynecol 44:487–491 - DOI
    1. Kitade M, Takeuchi H, Kikuchi I, Shimanuki H, Kumakiri J, Kinoshita K (2005) A case of simultaneous tubal-splenic pregnancy after assisted reproductive technology. Fertil Steril 83(4):1042. https://doi.org/10.1016/j.fertnstert.2004.10.047 - DOI - PubMed

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