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. 1977 Jun;74(6):2321-4.
doi: 10.1073/pnas.74.6.2321.

The complete amino acid sequence of prochymosin

B Foltmann, V B Pedersen, H Jacobsen, D Kauffman, G Wybrandt

The complete amino acid sequence of prochymosin

B Foltmann et al. Proc Natl Acad Sci U S A. 1977 Jun.

Abstract

The total sequence of 365 amino acid residues in bovine prochymosin is presented. Alignment with the amino acid sequence of porcine pepsinogen shows that 204 amino acid residues are common to the two zymogens. Further comparison and alignment with the amino acid sequence of penicillopepsin shows that 66 residues are located at identical positions in all three proteases. The three enzymes belong to a large group of proteases with two aspartate residues in the active center. This group forms a family derived from one common ancestor.

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References

    1. Acta Chem Scand B. 1976;30(10):979-84 - PubMed
    1. Biochem Biophys Res Commun. 1975 Apr 21;63(4):1106-12 - PubMed
    1. FEBS Lett. 1970 Feb 25;6(4):312-314 - PubMed
    1. Eur J Biochem. 1975 Jun 16;55(1):95-103 - PubMed
    1. FEBS Lett. 1974 Jul 15;43(2):207-11 - PubMed

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