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Case Reports
. 2020 Sep 14;20(1):244.
doi: 10.1186/s12890-020-01285-6.

Severe hemoptysis in post-tuberculosis bronchiectasis precipitated by SARS-CoV-2 infection

Julien Lopinto  1 , Marion Teulier  2 , Audrey Milon  3 , Guillaume Voiriot  2 , Muriel Fartoukh  2
Affiliations
Case Reports

Severe hemoptysis in post-tuberculosis bronchiectasis precipitated by SARS-CoV-2 infection

Julien Lopinto et al. BMC Pulm Med. .

Abstract

Background: Since the beginning of SARS-CoV-2 outbreak in China, severe acute respiratory syndrome has been widely descripted. Hemoptysis has rarely been observed in SARS-CoV-2 infection. We report here a case of severe hemoptysis in post-tuberculosis bronchiectasis precipitated by SARS-CoV-2 infection and managed in a referral center.

Case presentation: A 58-year-old man was admitted to our intensive care unit for severe hemoptysis with history of post-tuberculosis bronchiectasis. At ICU admission the patient had fever and severe acute respiratory failure requiring high flow oxygen therapy. Respiratory tract sampling was positive for SARS-CoV-2. Multi-detector computed tomography angiography pointed out localized bronchiectasis on the left lower lobe and enlarged left bronchial and phrenic arteries; bronchial arteriography with distal embolization was performed with favorable outcome and no bleeding recurrence.

Conclusions: To our knowledge, this is the first case of acute exacerbation of bronchiectasis related to SARS-CoV-2 infection and complicated by severe hemoptysis. Whether the virus may play a role in the dysregulation of airway haemostasis, and contribute to episodes of hemoptysis in patients with chronic pulmonary diseases and predisposing factors might be investigated.

Keywords: Bronchiectasis; Case report; SARS-CoV-2; Severe hemoptysis.

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Conflict of interest statement

Authors have reported that no potential conflicts of interest exist with any companies/organizations whose products or services may be discussed in this article.

Figures

Fig. 1
Fig. 1
a Coronal CT section showing enlarged left bronchial artery (red arrow). b Axial CT section showing enlarged left phrenic artery (arrow)
See this image and copyright information in PMC

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