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Comment
. 2020 Sep 14;38(3):313-316.
doi: 10.1016/j.ccell.2020.08.013.

A Multi-layer Molecular Fresco of the Immune Diversity across Hematologic Malignancies

Davide Bedognetti  1
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Comment

A Multi-layer Molecular Fresco of the Immune Diversity across Hematologic Malignancies

Davide Bedognetti. Cancer Cell. .
Free article

Abstract

Immune checkpoint blockade has limited activity in the large majority of hematologic malignancies. In this issue of Cancer Cell, Dufva et al. provide an immunologic portrait of these heterogenous diseases and identify key relationships between oncogenic states and immune response that can spur the development of more efficient immunotherapeutic approaches.

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  • Immunogenomic Landscape of Hematological Malignancies.
    Dufva O, Pölönen P, Brück O, Keränen MAI, Klievink J, Mehtonen J, Huuhtanen J, Kumar A, Malani D, Siitonen S, Kankainen M, Ghimire B, Lahtela J, Mattila P, Vähä-Koskela M, Wennerberg K, Granberg K, Leivonen SK, Meriranta L, Heckman C, Leppä S, Nykter M, Lohi O, Heinäniemi M, Mustjoki S. Dufva O, et al. Cancer Cell. 2020 Sep 14;38(3):380-399.e13. doi: 10.1016/j.ccell.2020.06.002. Epub 2020 Jul 9. Cancer Cell. 2020. PMID: 32649887

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