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Editorial
. 2020 Sep 11;21(18):6651.
doi: 10.3390/ijms21186651.

Facts about Fats: New Insights into the Role of Lipids in Metabolism, Disease and Therapy

Marco Segatto  1 , Valentina Pallottini  2
Affiliations
Editorial

Facts about Fats: New Insights into the Role of Lipids in Metabolism, Disease and Therapy

Marco Segatto et al. Int J Mol Sci. .

Abstract

Although initially regarded as a passive system to store energy, lipids are now considered to play crucial, structural and functional roles in almost all the biological processes involved in the regulation of physiological and pathological conditions [...].

Keywords: Cholesterol; Fatty acids; Lipid mediators; Lipids; Lipophagy; Sphingolipids.

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Conflict of interest statement

The authors declare no conflict of interest.

References

    1. Escribá P.V., González-Ros J.M., Goñi F.M., Kinnunen P.K., Vigh L., Sánchez-Magraner L., Fernández A.M., Busquets X., Horváth I., Barceló-Coblijn G. Membranes: A meeting point for lipids, proteins and therapies. J. Cell Mol. Med. 2008;12:829–875. doi: 10.1111/j.1582-4934.2008.00281.x. - DOI - PMC - PubMed
    1. Kuller L.H. Nutrition, lipids, and cardiovascular disease. Nutr. Rev. 2006;64:S15–S26. doi: 10.1111/j.1753-4887.2006.tb00230.x. - DOI - PubMed
    1. Butler L.M., Perone Y., Dehairs J., Lupien L.E., de Laat V., Talebi A., Loda M., Kinlaw W.B., Swinnen J.V. Lipids and cancer: Emerging roles in pathogenesis, diagnosis and therapeutic intervention. Adv. Drug Deliv. Rev. 2020 doi: 10.1016/j.addr.2020.07.013. - DOI - PMC - PubMed
    1. Pesiri V., Totta P., Segatto M., Bianchi F., Pallottini V., Marino M., Acconcia F. Estrogen receptor α L429 and A430 regulate 17β-estradiol-induced cell proliferation via CREB1. Cell. Signal. 2015;27:2380–2388. doi: 10.1016/j.cellsig.2015.08.021. - DOI - PubMed
    1. Cartocci V., Segatto M., Di Tunno I., Leone S., Pfrieger F.W., Pallottini V. Modulation of the Isoprenoid/Cholesterol Biosynthetic Pathway During Neuronal Differentiation In Vitro. J. Cell Biochem. 2016;117:2036–2044. doi: 10.1002/jcb.25500. - DOI - PubMed

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