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Review
. 2020 Sep 15;5(1):203.
doi: 10.1038/s41392-020-00310-8.

Convalescent plasma therapy for COVID-19: a tried-and-true old strategy?

Yongzhi Xi  1
Affiliations
Review

Convalescent plasma therapy for COVID-19: a tried-and-true old strategy?

Yongzhi Xi. Signal Transduct Target Ther. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

The author declares no competing interests.

Figures

Fig. 1
Fig. 1. The immune mechanisms of ADE mediated by viral infections.
a–c Mechanisms underlying the antibody-dependent enhancement (ADE) of viral infections mediated by the Fcγ receptor and complement-dependent pathways, and the relationship between ADE occurrence and antibody titer. Figure partially adapted from ref.
See this image and copyright information in PMC

References

    1. WHO. Coronavirus Disease 2019 (COVID-19) Situation Report-209 (World Health Organization, Geneva, 2020).
    1. Baden LR, Rubin EJ. Covid-19—the search for effective therapy. N. Engl. J. Med. 2020;382:1851–1852. doi: 10.1056/NEJMe2005477. - DOI - PMC - PubMed
    1. National Health Commission of the People’s Republic of China. Official Guidance for Prevention, Control, Diagnosis and Management for COVID-19 Patients (version 6.0). http://www.nhc.gov.cn/yzygj/s7653p/202002/8334a8326dd94d329df351d7da8aef... (2020) (in Chinese).
    1. NIH. Coronavirus Disease 2019 (COVID-19) Treatment Guidelines (2020) (NIH, 2020). - PubMed
    1. Shen C, et al. Treatment of 5 critically ill patients with COVID-19 with convalescent plasma. JAMA. 2020;323:1582–1589. doi: 10.1001/jama.2020.4783. - DOI - PMC - PubMed

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