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Review
. 2020 Dec;9(23):e2000735.
doi: 10.1002/adhm.202000735. Epub 2020 Sep 16.

Silk-Based Biomaterials for Cardiac Tissue Engineering

Yu Song  1   2 , Huifang Wang  1   2 , Feifei Yue  1   2 , Qiying Lv  2 , Bo Cai  2 , Nianguo Dong  3 , Zheng Wang  1   4 , Lin Wang  1   2
Affiliations
Review

Silk-Based Biomaterials for Cardiac Tissue Engineering

Yu Song et al. Adv Healthc Mater. 2020 Dec.

Abstract

Cardiovascular diseases are one of the leading causes of death globally. Among various cardiovascular diseases, myocardial infarction is an important one. Compared with conventional treatments, cardiac tissue engineering provides an alternative to repair and regenerate the injured tissue. Among various types of materials used for tissue engineering applications, silk biomaterials have been increasingly utilized due to their biocompatibility, biological functions, and many favorable physical/chemical properties. Silk biomaterials are often used alone or in combination with other materials in the forms of patches or hydrogels, and serve as promising delivery systems for bioactive compounds in tissue engineering repair scenarios. This review focuses primarily on the promising characteristics of silk biomaterials and their recent advances in cardiac tissue engineering.

Keywords: cardiac tissue engineering; cardiovascular diseases; sericin; silk materials.

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