Nutrient regulation of somatic growth in teleost fish. The interaction between somatic growth, feeding and metabolism

Abstract

This review covers the current knowledge on the regulation of the somatic growth axis and its interaction with metabolism and feeding regulation. The main endocrine and neuroendocrine factors regulating both the growth axis and feeding behavior will be briefly summarized. Recently discovered neuropeptides and peptide hormones will be mentioned in relation to feeding control as well as growth hormone regulation. In addition, the influence of nutrient and nutrient sensing mechanisms on growth axis will be highlighted. We expect that in this process gaps of knowledge will be exposed, stimulating future research in those areas.

Keywords: Dietary composition; Growth hormone; Hypothalamus; IGF; Neuroendocrine regulation; Nutrient sensing mechanisms.