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. 2020 Sep 17;18(1):104.
doi: 10.1186/s12961-020-00619-4.

Transforming the practice of medicine through team science

Jason H Pitzen  1 , Heidi L Dieter  2 , Darren L Gronseth  2 , Amber K Dahl  2 , Venessa L Boyle  3 , Tharana Maran  3 , C Michel Harper Jr  4 , Gregory J Gores  5
Affiliations

Transforming the practice of medicine through team science

Jason H Pitzen et al. Health Res Policy Syst. .

Abstract

Background: The translation of biomedical research discoveries into clinical practice is marked by extended timelines (averaging 17 years) and multiple sequential process steps. However, even after a drug, device, diagnostic tool or unique therapeutic procedure successfully navigates through clinical testing to approval, real barriers remain in applying and scaling the innovation in practice.

Methods: Mayo Clinic initiated the Transform the Practice programme to facilitate multidisciplinary team and convergence science to continuously reinvent solutions to address unmet patient needs and accelerate the application of next-generation healthcare solutions. During a 5-year period, 24 programme teams received financial resources, barrier-removing engagement from clinical and research leadership, and enhanced administrative support, including dedicated project managers.

Results: The approach created value in facilitating consistent progress toward project objectives and resulted in multiple publications, new extramural funding sources, and implementation of new tests and services into the clinical practice. This report describes the concentrated institutional effort to accelerate the discovery-translation-application continuum in an academic medical centre and highlights successful applications and persistent obstacles.

Conclusions: The Transform the Practice approach is effective in moving high-potential research discoveries closer to implementation in the clinical practice. Its concepts, including the application of structured project management methodology, may be quickly integrated to shorten an organisation's time to implementing its most important discoveries.

Keywords: Diffusion of innovation; Organisational innovation; Translational medical research.

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Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Fig. 1
Fig. 1
Translational readiness level
Fig. 2
Fig. 2
Strengths, Weaknesses, Opportunities or Threats analysis. PI principal investigator, PM project manager, TtP Transform the Practice
Fig. 3
Fig. 3
a Outcomes of Transform the Practice team projects. Outcomes were assessed in 2018 and 2019; teams were formed from 2014 through 2018. b Interdisciplinary teams supported by Transform the Practice
See this image and copyright information in PMC

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