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Comment
. 2021 Jan;79(1):161-162.
doi: 10.1016/j.eururo.2020.08.017. Epub 2020 Sep 14.

Re: Regenerative Potential of Prostate Luminal Cells Revealed by Single-cell Analysis

Natasha Kyprianou  1
Affiliations
Comment

Re: Regenerative Potential of Prostate Luminal Cells Revealed by Single-cell Analysis

Natasha Kyprianou. Eur Urol. 2021 Jan.
No abstract available

PubMed Disclaimer

Conflict of interest statement

Conflicts of interest: The author has nothing to disclose.

Comment on

  • Regenerative potential of prostate luminal cells revealed by single-cell analysis.
    Karthaus WR, Hofree M, Choi D, Linton EL, Turkekul M, Bejnood A, Carver B, Gopalan A, Abida W, Laudone V, Biton M, Chaudhary O, Xu T, Masilionis I, Manova K, Mazutis L, Pe'er D, Regev A, Sawyers CL. Karthaus WR, et al. Science. 2020 May 1;368(6490):497-505. doi: 10.1126/science.aay0267. Science. 2020. PMID: 32355025 Free PMC article.

References

    1. Kyprianou N, Isaacs JT. Activation of programmed cell death in the rat ventral prostate following castration. Endocrinology 1988;122:552–62. - PubMed
    1. Isaacs JT. Prostate stem cells and benign prostatic hyperplasia. Prostate 2008;68:1025–34. - PMC - PubMed
    1. Wang X, Kruithof-de Julio M, Economides KD, et al. A luminal epithelial stem cell that is a cell of origin for prostate cancer. Nature 2009;461:495–500. - PMC - PubMed
    1. Barros-Silva JD, Linn DE, Steiner I, et al. Single-cell analysis identifies LY6D as a marker linking castration-resistant prostate luminal cells to prostate progenitors and cancer. Cell Rep 2018;25, 3504–18.e6. - PMC - PubMed
    1. Ku SY, Rosario S, Wang Y, et al. Rb1 and Trp53 cooperate to suppress prostate cancer lineage plasticity, metastasis, and antiandrogen resistance. Science 2017;355:78–83. - PMC - PubMed