Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2020 Sep 15;117(37):22653-22654.
doi: 10.1073/pnas.2013790117.

Functional actin cytoskeleton is required in early stage of NETosis induction

Affiliations
Comment

Functional actin cytoskeleton is required in early stage of NETosis induction

Ming-Lin Liu. Proc Natl Acad Sci U S A. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

The author declares no competing interest.

Figures

Fig. 1.
Fig. 1.
Histograms of flow cytometry analysis of actin polymerization (F-actin detected by RFP-labeled phalloidin) of PMA-treated HL60 cells at 0, 60, and 180 min.

Comment in

Comment on

References

    1. Thiam H. R., et al. ., NETosis proceeds by cytoskeleton and endomembrane disassembly and PAD4-mediated chromatin decondensation and nuclear envelope rupture. Proc. Natl. Acad. Sci. U.S.A. 117, 7326–7337 (2020). - PMC - PubMed
    1. Neeli I., Dwivedi N., Khan S., Radic M., Regulation of extracellular chromatin release from neutrophils. J. Innate Immun. 1, 194–201 (2009). - PMC - PubMed
    1. Neubert E., Meyer D., Kruss S., Erpenbeck L., The power from within − Understanding the driving forces of neutrophil extracellular trap formation. J. Cell Sci. 133, jcs241075 (2020). - PubMed
    1. Stojkov D., et al. ., ROS and glutathionylation balance cytoskeletal dynamics in neutrophil extracellular trap formation. J. Cell Biol. 216, 4073–4090 (2017). - PMC - PubMed
    1. Metzler K. D., Goosmann C., Lubojemska A., Zychlinsky A., Papayannopoulos V., A myeloperoxidase-containing complex regulates neutrophil elastase release and actin dynamics during NETosis. Cell Rep. 8, 883–896 (2014). - PMC - PubMed

LinkOut - more resources