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Comment
. 2020 Nov;19(11):755.
doi: 10.1038/d41573-020-00165-2.

Selectively triggering mitotic failure

Comment

Selectively triggering mitotic failure

Sarah Crunkhorn. Nat Rev Drug Discov. 2020 Nov.
No abstract available

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  • TRIM37 controls cancer-specific vulnerability to PLK4 inhibition.
    Meitinger F, Ohta M, Lee KY, Watanabe S, Davis RL, Anzola JV, Kabeche R, Jenkins DA, Shiau AK, Desai A, Oegema K. Meitinger F, et al. Nature. 2020 Sep;585(7825):440-446. doi: 10.1038/s41586-020-2710-1. Epub 2020 Sep 9. Nature. 2020. PMID: 32908304 Free PMC article.
  • Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.
    Yeow ZY, Lambrus BG, Marlow R, Zhan KH, Durin MA, Evans LT, Scott PM, Phan T, Park E, Ruiz LA, Moralli D, Knight EG, Badder LM, Novo D, Haider S, Green CM, Tutt ANJ, Lord CJ, Chapman JR, Holland AJ. Yeow ZY, et al. Nature. 2020 Sep;585(7825):447-452. doi: 10.1038/s41586-020-2690-1. Epub 2020 Sep 9. Nature. 2020. PMID: 32908313 Free PMC article.

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References

    1. Yeow, Z. et al.Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer. Nature https://doi.org/10.1038/s41586-020-2690-1 (2020)
    1. Meitinger, F. et al. TRIM37 controls cancer-specific vulnerability to PLK4 inhibition. Nature https://doi.org/10.1038/s41586-020-2710-1 (2020)

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