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Comment
. 2020 Dec;17(12):719-720.
doi: 10.1038/s41571-020-00433-5.

Validation of plasma-derived small extracellular vesicles as cancer biomarkers

Affiliations
Comment

Validation of plasma-derived small extracellular vesicles as cancer biomarkers

Theresa L Whiteside. Nat Rev Clin Oncol. 2020 Dec.
No abstract available

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Comment on

  • Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers.
    Hoshino A, Kim HS, Bojmar L, Gyan KE, Cioffi M, Hernandez J, Zambirinis CP, Rodrigues G, Molina H, Heissel S, Mark MT, Steiner L, Benito-Martin A, Lucotti S, Di Giannatale A, Offer K, Nakajima M, Williams C, Nogués L, Pelissier Vatter FA, Hashimoto A, Davies AE, Freitas D, Kenific CM, Ararso Y, Buehring W, Lauritzen P, Ogitani Y, Sugiura K, Takahashi N, Alečković M, Bailey KA, Jolissant JS, Wang H, Harris A, Schaeffer LM, García-Santos G, Posner Z, Balachandran VP, Khakoo Y, Raju GP, Scherz A, Sagi I, Scherz-Shouval R, Yarden Y, Oren M, Malladi M, Petriccione M, De Braganca KC, Donzelli M, Fischer C, Vitolano S, Wright GP, Ganshaw L, Marrano M, Ahmed A, DeStefano J, Danzer E, Roehrl MHA, Lacayo NJ, Vincent TC, Weiser MR, Brady MS, Meyers PA, Wexler LH, Ambati SR, Chou AJ, Slotkin EK, Modak S, Roberts SS, Basu EM, Diolaiti D, Krantz BA, Cardoso F, Simpson AL, Berger M, Rudin CM, Simeone DM, Jain M, Ghajar CM, Batra SK, Stanger BZ, Bui J, Brown KA, Rajasekhar VK, Healey JH, de Sousa M, Kramer K, Sheth S, Baisch J, Pascual V, Heaton TE, La Quaglia MP, Pisapia DJ, Schwartz R, Zhang H, Liu Y, Shukla A, Blavier L, DeClerck YA, LaBarge M, Bissell MJ, Caffrey TC, Grandgenett PM, Hollingsw… See abstract for full author list ➔ Hoshino A, et al. Cell. 2020 Aug 20;182(4):1044-1061.e18. doi: 10.1016/j.cell.2020.07.009. Epub 2020 Aug 13. Cell. 2020. PMID: 32795414 Free PMC article.

References

    1. Theodoraki, M. N. et al. Significance of PD-L1( + ) exosomes in plasma of head and neck cancer patients. Clin. Cancer Res. 24, 896–905 (2018). - DOI
    1. Chen, G. et al. Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response. Nature 560, 382–386 (2018). - DOI
    1. Theodoraki, M. N. et al. Circulating exosomes measure responses to therapy in head and neck cancer patients treated with cetuximab, ipilimumab, and IMRT. Oncoimmunology 8, 1593805 (2019). - DOI
    1. Whiteside, T. L. The potential of tumor-derived exosomes for noninvasive cancer monitoring: an update. Expert Rev. Mol. Diagn. 18, 1029–1040 (2018). - DOI
    1. Kalluri R. The biology and function of exosomes in cancer. J. Clin. Invest. 126, 1208–1215

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