How severe COVID-19 infection is changing ARDS management

Niall D Ferguson^{1

2

3

4}, Tài Pham^{5

6

7}, Michelle Ng Gong^{8

9}

Affiliations

¹ Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Canada. n.ferguson@utoronto.ca.
² Departments of Medicine, Physiology, Institute for Health Policy, Management and Evaluation, University of Toronto, Toronto, Canada. n.ferguson@utoronto.ca.
³ Department of Medicine, Division of Respirology and Critical Care, University Health Network and Sinai Health, Toronto, Canada. n.ferguson@utoronto.ca.
⁴ Toronto General Hospital Research Institute, 585 University Ave, 11-PMB-120, Toronto, ON, M5G 2N2, Canada. n.ferguson@utoronto.ca.
⁵ Service de Médecine Intensive-Réanimation, AP-HP, Hôpital de Bicêtre, Hôpitaux Universitaires Paris-Saclay, Le Kremlin-Bicêtre, France.
⁶ Faculté de Médecine, Université Paris-Saclay, Le Kremlin-Bicêtre, France.
⁷ Équipe d'Épidémiologie Respiratoire Intégrative, Center for Epidemiology and Population Health (CESP), Université Paris-Saclay, UVSQ, Univ. Paris-Sud, Inserm, Villejuif, France.
⁸ Division of Critical Care Medicine, Division of Pulmonary Medicine, Department of Medicine, Montefiore Medical Center, Albert Einstein College of Medicine, New York, NY, USA.
⁹ Department of Epidemiology and Population Health, Albert Einstein College of Medicine, New York, NY, USA.

Editorial

Niall D Ferguson et al. Intensive Care Med. 2020 Dec.

. 2020 Dec;46(12):2184-2186.

doi: 10.1007/s00134-020-06245-6. Epub 2020 Sep 18.

Niall D Ferguson^{1

2

3

4}, Tài Pham^{5

6

7}, Michelle Ng Gong^{8

9}

¹ Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Canada. n.ferguson@utoronto.ca.
² Departments of Medicine, Physiology, Institute for Health Policy, Management and Evaluation, University of Toronto, Toronto, Canada. n.ferguson@utoronto.ca.
³ Department of Medicine, Division of Respirology and Critical Care, University Health Network and Sinai Health, Toronto, Canada. n.ferguson@utoronto.ca.
⁴ Toronto General Hospital Research Institute, 585 University Ave, 11-PMB-120, Toronto, ON, M5G 2N2, Canada. n.ferguson@utoronto.ca.
⁵ Service de Médecine Intensive-Réanimation, AP-HP, Hôpital de Bicêtre, Hôpitaux Universitaires Paris-Saclay, Le Kremlin-Bicêtre, France.
⁶ Faculté de Médecine, Université Paris-Saclay, Le Kremlin-Bicêtre, France.
⁷ Équipe d'Épidémiologie Respiratoire Intégrative, Center for Epidemiology and Population Health (CESP), Université Paris-Saclay, UVSQ, Univ. Paris-Sud, Inserm, Villejuif, France.
⁸ Division of Critical Care Medicine, Division of Pulmonary Medicine, Department of Medicine, Montefiore Medical Center, Albert Einstein College of Medicine, New York, NY, USA.
⁹ Department of Epidemiology and Population Health, Albert Einstein College of Medicine, New York, NY, USA.

No abstract available

Conflict of interest statement

Dr. Ferguson reports personal fees from Xenios and Getinge, outside the submitted work.

1. Bellani G, et al. Epidemiology, patterns of care, and mortality for patients with acute respiratory distress syndrome in intensive care units in 50 countries. JAMA. 2016;315:788–800. doi: 10.1001/jama.2016.0291. - DOI - PubMed
1. The National Heart Lung, and Blood Institute PETAL Clinical Trials Network Early neuromuscular blockade in the acute respiratory distress syndrome. New Engl J Med. 2019;380:1997–2008. doi: 10.1056/NEJMoa1901686. - DOI - PMC - PubMed
1. Guérin C, et al. A prospective international observational prevalence study on prone positioning of ARDS patients: the APRONET (ARDS Prone Position Network) study. Intensive Care Med. 2018;44:22–37. doi: 10.1007/s00134-017-4996-5. - DOI - PubMed
1. Cummings MJ, et al. Epidemiology, clinical course, and outcomes of critically ill adults with COVID-19 in New York City: a prospective cohort study. Lancet. 2020 doi: 10.1016/s0140-6736(20)31189-2. - DOI - PMC - PubMed
1. Coppo A, et al. Feasibility and physiological effects of prone positioning in non-intubated patients with acute respiratory failure due to COVID-19 (PRON-COVID): a prospective cohort study. Lancet Respir Med. 2020 doi: 10.1016/s2213-2600(20)30268-x. - DOI - PMC - PubMed