Role of Intralesional Antibiotic for Treatment of Subretinal Abscess - Case Report and Literature Review

Abstract

Purpose: To describe a rare case of endogenous endophthalmitis due to Citrobacter with subretinal abscess and the role of the novel technique of intralesional antibiotic for its treatment.

Methods: A retrospective case report.

Result: A 45-year-old male presenting with painful, progressive diminution of vision in the left eye was diagnosed to have endogenous endophthalmitis due to Citrobacter with subretinal abscess. After the failure of the initial intravitreal injection of ceftazidime and vancomycin, successful resolution of abscess was achieved by pars plana vitrectomy with 41-gauge (G) needle assisted intralesional injection of piperacillin and tazobactam combination.

Conclusion: We treated a case of Citrobacter associated endogenous endophthalmitis with subretinal abscess with intralesional injection of piperacillin and tazobactam combination. 41-G needle can be used safely to inject antibiotic into the subretinal space through a small self-sealing retinotomy with minimum risk of retinal detachment and encouraging results.

Keywords: 41-gauge injection; Endogenous endophthalmitis; citrobacter; intralesional injection; piperacillin; subretinal abscess; tazobactam.