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Case Reports
. 2020 Nov-Dec;8(10):3594-3596.e3.
doi: 10.1016/j.jaip.2020.08.059. Epub 2020 Sep 15.

Three patients with X-linked agammaglobulinemia hospitalized for COVID-19 improved with convalescent plasma

Haoli Jin  1 , James C Reed  2 , Sean T H Liu  3 , Hsi-En Ho  1 , Joao Pedro Lopes  1 , Nicole B Ramsey  1 , Omar Waqar  1 , Farah Rahman  3 , Judith A Aberg  3 , Nicole M Bouvier  4 , Charlotte Cunningham-Rundles  5 ; Mount Sinai Health System Convalescent Plasma Team
Collaborators, Affiliations
Case Reports

Three patients with X-linked agammaglobulinemia hospitalized for COVID-19 improved with convalescent plasma

Haoli Jin et al. J Allergy Clin Immunol Pract. 2020 Nov-Dec.
No abstract available

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Figures

Figure 1
Figure 1
CT Chest images for (A) patient 1, (B) 2, and (C) 3, respectively, showing diffuse bilateral ground-glass opacities.
Figure E1
Figure E1
Clinical course of patients. BAL, Bronchoalveolar lavage; C diff, Clostridium difficile; CXR, chest X-ray; ECHO, echocardiogram; ED, emergency department; GGO, ground-glass opacities; LLL, left lower lobe; LMCA, left main coronary artery; MRI, magnetic resonance imaging; NP, nasopharyngeal; PCP, primary care physician; pRBC, packed red blood cell; resp., respiratory; RLL, right lower lobe; RML, right middle lobe; SMX-TMP, sulfamethoxazole-trimethoprim; US, ultrasound.
Figure E1
Figure E1
Clinical course of patients. BAL, Bronchoalveolar lavage; C diff, Clostridium difficile; CXR, chest X-ray; ECHO, echocardiogram; ED, emergency department; GGO, ground-glass opacities; LLL, left lower lobe; LMCA, left main coronary artery; MRI, magnetic resonance imaging; NP, nasopharyngeal; PCP, primary care physician; pRBC, packed red blood cell; resp., respiratory; RLL, right lower lobe; RML, right middle lobe; SMX-TMP, sulfamethoxazole-trimethoprim; US, ultrasound.
See this image and copyright information in PMC

References

    1. Bloch E.M., Shoham S., Casadevall A., Sachais B.S., Shaz B., Winters J.L. Deployment of convalescent plasma for the prevention and treatment of COVID-19. J Clin Invest. 2020;130:2757–2765. - PMC - PubMed
    1. Joyner M.J., Wright R.S., Fairweather D., Senefeld J.W., Bruno K.A., Klassen S.A. Early safety indicators of COVID-19 convalescent plasma in 5,000 patients. J Clin Invest. 2020;130:4791–4797. - PMC - PubMed
    1. Shen C., Wang Z., Zhao F., Yang Y., Li J., Yuan J. Treatment of 5 critically ill patients with COVID-19 with convalescent plasma. JAMA. 2020;323:1582–1589. - PMC - PubMed
    1. Duan K., Liu B., Li C., Zhang H., Yu T., Qu J. Effectiveness of convalescent plasma therapy in severe COVID-19 patients. Proc Natl Acad Sci U S A. 2020;117:9490–9496. - PMC - PubMed
    1. Ye M., Fu D., Ren Y., Wang F., Wang D., Zhang F. Treatment with convalescent plasma for COVID-19 patients in Wuhan, China. J Med Virol. 2020;92:1890–1901. - PMC - PubMed

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